Polyploidization and Cancer (Record no. 110591)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02588nam a22004215i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-4419-6199-0 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20140220084509.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 120403s2010 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781441961990 |
| -- | 978-1-4419-6199-0 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-4419-6199-0 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | R-RZ |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MBGR |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED000000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 610 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Poon, Randy Y. C. |
| Relator term | editor. |
| 245 10 - TITLE STATEMENT | |
| Title | Polyploidization and Cancer |
| Medium | [electronic resource] / |
| Statement of responsibility, etc | edited by Randy Y. C. Poon. |
| 264 #1 - | |
| -- | New York, NY : |
| -- | Springer New York, |
| -- | 2010. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XVI, 148p. 36 illus., 1 illus. in color. |
| Other physical details | online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Advances in Experimental Medicine and Biology, |
| International Standard Serial Number | 0065-2598 ; |
| Volume number/sequential designation | 676 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Polyploidy, Aneuploidy and the Evolution of Cancer -- Molecular Mechanisms and Function of the Spindle Checkpoint, a Guardian of the Chromosome Stability -- Understanding Cytokinesis Failure -- DNA Damage and Polyploidization -- Role of the p53 Family in Stabilizing the Genome and Preventing Polyploidization -- Centrosomes, Polyploidy and Cancer -- Polyploidy: Mechanisms and Cancer Promotion in Hematopoietic and Other Cells -- Polyploidization of liver cells -- Analysis of Cellular DNA Content by Flow and Laser Scanning Cytometry. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overview subjects relating to polyploidization and cancer. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine general. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9781441961983 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Advances in Experimental Medicine and Biology, |
| -- | 0065-2598 ; |
| Volume number/sequential designation | 676 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://dx.doi.org/10.1007/978-1-4419-6199-0 |
| 912 ## - | |
| -- | ZDB-2-SBL |
No items available.