000 03852nam a22004575i 4500
001 978-94-007-6220-6
003 DE-He213
005 20140220082941.0
007 cr nn 008mamaa
008 130603s2013 ne | s |||| 0|eng d
020 _a9789400762206
_9978-94-007-6220-6
024 7 _a10.1007/978-94-007-6220-6
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aHaim, Abraham.
_eauthor.
245 1 0 _aLight Pollution as a New Risk Factor for Human Breast and Prostate Cancers
_h[electronic resource] /
_cby Abraham Haim, Boris A. Portnov.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2013.
300 _aVIII, 168 p. 26 illus., 16 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPreface -- Introduction -- PART 1: ARTIFICIAL LIGHT AND HUMAN TEMPORAL ORGANIZATION -- Artificial light and its physicochemical properties (by Fabio Falchi) -- Light and dark cycles as a basis of temporal organization -- The biological clock and its entrainment by photoperiod -- LAN exposure and its potential effects on daily rhythms and seasonal disruptions -- Melatonin (MLT) –“hormone of darkness” and a “jack of all traits” -- PART II: LIGHT POLLUTION, ITS KNOWN HEALTH EFFECTS AND IMPACT ON ENERGY CONSERVATION -- Introduction and spread of artificial illumination – a human history retrospective -- Biological definition of light pollution -- Light pollution as a general stressor -- The effects of light pollution on animal rhythms and ecology -- Light pollution and hormone-dependent cancers: summary of accumulated empirical evidence -- PART III: LIGHT POLLUTION AND ITS POTENTIAL LINKS TO BREAST AND PROSTATE CANCERS -- Geographic patterns of breast and prostate cancers (BC&PC) worldwide -- Light pollution and its association with breast and prostate cancers (BC&PC) in population-level studies -- Selected methodological issues of Light-at-Night (LAN) – Breast and Prostate Cancers (BC&PC) research -- Dark-less world – what is next? (Conclusions and prospects for future research) -- BIBLIOGRAPHY -- ADDITIONAL READING.
520 _aHumans are diurnal organisms whose biological clock and temporal organization depend on natural light/dark cycles. Changes in the photoperiod are a signal for seasonal acclimatization of physiological and immune systems as well as behavioral patterns. The invention of electrical light bulbs created more opportunities for work and leisure. However, exposure to artificial light at night (LAN) affects our biological clock, and suppresses pineal melatonin (MLT) production. Among its other properties, MLT is an antioncogenic agent, and therefore its suppression increases the risks of developing breast and prostate cancers (BC&PC). To the best of our knowledge, this book is the first to address the linkage between light pollution and BC&PC in humans. It explains several state-of-the-art theories, linking light pollution with BC&PC. It also illustrates research hypotheses about health effects of light pollution using the results of animal models and population-based studies.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aEnvironmental Medicine.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aEnvironmental Health.
650 2 4 _aBiomedicine general.
700 1 _aPortnov, Boris A.
_eauthor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789400762190
856 4 0 _uhttp://dx.doi.org/10.1007/978-94-007-6220-6
912 _aZDB-2-SBL
999 _c99841
_d99841