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001 978-94-007-6214-5
003 DE-He213
005 20140220082941.0
007 cr nn 008mamaa
008 130228s2013 ne | s |||| 0|eng d
020 _a9789400762145
_9978-94-007-6214-5
024 7 _a10.1007/978-94-007-6214-5
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aFang, Evandro Fei.
_eeditor.
245 1 0 _aAntitumor Potential and other Emerging Medicinal Properties of Natural Compounds
_h[electronic resource] /
_cedited by Evandro Fei Fang, Tzi Bun Ng.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2013.
300 _aXIX, 423 p. 37 illus., 26 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPREFACE -- PART I. Lectins: From biological recognition molecules to variable medicinal applications -- Lectins: Personal Comments of Nathan Sharon Taken from His Memoirs (Translation from Hebrew) .-The History of Lectinology -- Animal and Human Lectins -- Lectins of Marine Origin and their Clinical Applications -- Medicinal applications of plant lectins -- PART II Structural and functional insights into medicinal ribonucleases -- Plant nucleases from nuclease I family: their properties and antitumor potential -- Bovine Seminal Ribonuclease and its special features: when two is better than one -- PART III The perspectives for ribosome inactivating proteins: unveiling the working mechanisms and potential medicinal benefits -- The Discovery of MAP30 and Elucidation of its Medicinal Activities -- Ribosome Inactivating Proteins from Plants: Biological Properties and their Use in Experimental Therapy -- Current status & Biomedical applications of Ribosome-inactivating proteins -- PART IV The research history of protease inhibitors and their health implications -- The Health Benefits of the Bowman-Birk Inhibitor -- Peptidic inhibitors of serine proteinases of plant origin -- Anti-tumor effect of synthetic serine protease inhibitor.-  A landscape of the health benefits of different natural protease inhibitors -- PART V Plethora of health benefits from small molecules: From bench-top to clinical settings -- Autophagy upregulation as a therapeutic strategy for neurodegenerative diseases -- Rapamycin – current and future uses -- Eating, drinking, smoking and cancer prevention: a focus on acetaldehyde -- The use of edible mushroom water soluble polysaccharides in the treatment and prevention of chronic diseases: a mechanistic approach -- Essential Oil Constituents: Biodiversity and their Applicability for Cancer Therapy -- PART VI Medicinal compounds from the garden: a bird’s eye view of one mushroom, one fruit, one insect, and others -- Recent research on pharmacological activities of the medicinal fungus Cordyceps sinensis -- The bitter fruit with sweet health benefits:A comprehensive synopsis of recent research progress on medicinal properties of Momordica charantia -- Bioactive constituents of the silk worm Bombyx mori -- Proteins with anticancer and antimicobial activities from mammals, submammalian vertebrates and invertebrates -- Defense proteins with antiproliferative and antimicrobial activities from fungi and bacteria -- PART VII  Modernizing investigations of traditional Chinese medicine at the molecular level -- The role of the GP-TCM Research Association to modernization and globalization of Traditional Chinese Medicine.-  High-throughput screening in traditional Chinese medicine-based drug discovery -- PART VIII Questions and future perspectives -- Achievements, questions arising and future outlook on the path to discover new medicinal compounds. Index.
520 _aThe modern unhealthy diet and lifestyle in conjunction with pathogens, environmental carcinogens and multiple other risk factors increase humans’ susceptibility to different diseases exemplified by elevated levels of cancers, cardiovascular and communicable diseases. Screening of potential drugs from medicinal plants and animals provides a promising strategy for the alleviation of the impact of these diseases. Components with potential medicinal applications include RIPs, RNases, lectins, protease inhibitors and numerous small compounds. These compounds have shown both preventive and therapeutic effects for humans. This book is a compilation of articles written by internationally renowned experts exploring the different uses of medicinal compounds in human therapeutics. Here we provide a comprehensive outlook on both qualitative and quantitative studies focusing on medicinal plants and animals, and establishing a link between laboratory research discovery and clinical applications.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aToxicology.
650 0 _aCytology.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aApoptosis.
650 2 4 _aBiomedicine general.
650 2 4 _aMolecular Medicine.
650 2 4 _aPharmacology/Toxicology.
650 2 4 _aBiomedicine general.
700 1 _aNg, Tzi Bun.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789400762138
856 4 0 _uhttp://dx.doi.org/10.1007/978-94-007-6214-5
912 _aZDB-2-SBL
999 _c99839
_d99839