000			05269nam a22005775i 4500
001			978-94-007-1333-8
003			DE-He213
005			20140220082932.0
007			cr nn 008mamaa
008			120913s2013 ne | s |||| 0|eng d
020			_a9789400713338 _9978-94-007-1333-8
024	7		_a10.1007/978-94-007-1333-8 _2doi
050		4	_aRC321-580
072		7	_aPSAN _2bicssc
072		7	_aMED057000 _2bisacsh
082	0	4	_a612.8 _223
100	1		_aManto, Mario. _eeditor.
245	1	0	_aHandbook of the Cerebellum and Cerebellar Disorders _h[electronic resource] / _cedited by Mario Manto, Jeremy D. Schmahmann, Ferdinando Rossi, Donna L. Gruol, Noriyuki Koibuchi.
264		1	_aDordrecht : _bSpringer Netherlands : _bImprint: Springer, _c2013.
300			_aXXXIV, 2424 p. 450 illus., 400 illus. in color. eReference. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aChapter 1. Embryology -- Chapter 2. Anatomy -- Chapter 3. Neuroimaging of the cerebellum -- Chapter 4. Neurotransmitters and neuromodulators -- Chapter 5. Fructose metabolism and the cerebellum -- Chapter 6. Physiology of the cerebellum -- Chapter 7. Cerebellum and pain processing -- Chapter 8. Computational models of cerebellar function -- Chapter 9. Animal models of cerebellar ataxias -- Chapter 10. Symptoms of cerebellar disorders in human -- Chapter 11. Clinical deficits -- Chapter 12. Cerebellum and cognitive processes -- Chapter 13. Cerebellum and emotion regulation -- Chapter 14. Developmental disorders -- Chapter 15. Autism spectrum disorders and ataxia -- Chapter 16. Cerebellum and schizophrenia -- Chapter 17. Progressive myoclonic epilepsies -- Chapter 18. Cerebellar stroke -- Chapter 19. Immune diseases -- Chapter 20. Endocrine disorders -- Chapter 21. Infectious diseases -- Chapter 22. Tumors and paraneoplastic disorders -- Chapter 23. Trauma of the posterior fossa -- Chapter 24. Cerebellotoxic agents -- Chapter 25. Multiple system atrophy (MSA) -- Chapter 26. Essential tremor -- Chapter 27. Autosomal Recessive Cerebellar Ataxias (ARCAs) -- Chapter 28. Mitochondrial disorders -- Chapter 29. X-linked ataxias -- Chapter 30. Dominant ataxias -- Chapter 31. Overview of the differential diagnosis of cerebellar disorders -- Chapter 32. Overview of the general management of cerebellar disorders.
520			_aOur knowledge of cerebellar functions and cerebellar disorders, called ataxias, is increasing considerably. Studies of the cerebellum are now a central focus in neuroscience. During the last four decades, many laboratories worldwide have dedicated their research activities to understanding the roles of the cerebellum in motor control, cognitive processes and biology of mental processes, behavioral symptoms, and emotion. It is now accepted that the cerebellum acts as a cognitive operator in learning, perception, and attention. Moreover, major improvements in our assessment of in vivo cerebellar architecture using imaging techniques have occurred. A typical example is the accurate description of cerebellar anatomy during fetal development with MRI, a progress which has direct impacts on patient care. These advances have been associated with discoveries of new clinical disorders, in particular in the field of genetic ataxias. More than 20 new genes have been identified these last 10 years. Only for dominant ataxias, more than 30 diseases have now been unravelled. The number of ataxic disorders will increase with aging, the cerebellum being the structure of the brain with the most important loss of neurons with age. More than 300 different cerebellar disorders are encountered during daily practice, but we are missing a single source of information explaining their pathogenesis. Despite the immense amount of knowledge acquired about the cerebellar circuitry these last years, a large book covering the neuroscience of the cerebellum is missing. The goal of this endeavour is to bring up to date information relevant for basic science and also for clinical activities. To reach this goal, the most renowned authors are gathered in a unique and in-depth book with a format of a handbook. We emphasize the connections between molecular findings, imaging features, behavioural/neuropsychological aspects, and clinical implications.
650		0	_aMedicine.
650		0	_aHuman physiology.
650		0	_aNeurosciences.
650		0	_aNeurochemistry.
650		0	_aNeurology.
650		0	_aNeurosurgery.
650		0	_aNeurobiology.
650	1	4	_aBiomedicine.
650	2	4	_aNeurosciences.
650	2	4	_aNeurochemistry.
650	2	4	_aNeurobiology.
650	2	4	_aNeurology.
650	2	4	_aNeurosurgery.
650	2	4	_aHuman Physiology.
700	1		_aSchmahmann, Jeremy D. _eeditor.
700	1		_aRossi, Ferdinando. _eeditor.
700	1		_aGruol, Donna L. _eeditor.
700	1		_aKoibuchi, Noriyuki. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9789400713321
856	4	0	_uhttp://dx.doi.org/10.1007/978-94-007-1333-8
912			_aZDB-2-SBL
999			_c99355 _d99355