000 03270nam a22005175i 4500
001 978-3-642-39109-5
003 DE-He213
005 20140220082914.0
007 cr nn 008mamaa
008 130812s2013 gw | s |||| 0|eng d
020 _a9783642391095
_9978-3-642-39109-5
024 7 _a10.1007/978-3-642-39109-5
_2doi
050 4 _aTP248.13-248.65
072 7 _aTCB
_2bicssc
072 7 _aSCI010000
_2bisacsh
082 0 4 _a660.6
_223
100 1 _aYang, Chaoyong James.
_eeditor.
245 1 0 _aMolecular Beacons
_h[electronic resource] /
_cedited by Chaoyong James Yang, Weihong Tan.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2013.
300 _aIX, 194 p. 88 illus., 70 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aDesign, Synthesis, Purification and Characterization of Molecular Beacons -- Thermodynamic and Kinetic Properties of Molecular Beacons -- Application of Molecular Beacons in Real-Time PCR -- Molecular Beacons for Detection of Single Nucleotide Polymorphisms -- Molecular Beacons on Solid Surfaces -- Functional materials for signal amplification of molecular beacons -- Engineering Molecular Beacons for Advanced Applications -- Excimer Molecular Beacon -- Strategies for Delivering Molecular Beacons into Cells -- Molecular Beacons for Intracellular Analysis: Challenges and Successes -- Molecular Aptamer Beacons.
520 _aMolecular Beacons explains working principle of molecular beacons, discusses their design, synthesis, purification and characterization, explores their thermodynamic and kinetic properties, and more importantly, reviews their in vivo and in vitro applications with the emphasis on the design and modification of molecular beacons for in vivo mRNA imaging applications. This book is designed to bring together in a single resource an organized and comprehensive view of molecular beacons and will be a valuable resource for academic, clinical and industrial scientists and graduate students who may consider exploring molecular beacons in their research or practice. Chaoyong James Yang is the Lu Jiaxi Professor of Chemistry at Xiamen University, China. Weihong Tan is a Distinguished Professor of Chemistry and Biomedical Engineering at Hunan University, China and also a University of Florida Distinguished Professor and V. T. and Louis Jackson Professor of Chemistry at the University of Florida, USA.
650 0 _aChemistry.
650 0 _aGene expression.
650 0 _aAnalytical biochemistry.
650 0 _aBiotechnology.
650 0 _aNucleic acids.
650 0 _aCytology.
650 1 4 _aChemistry.
650 2 4 _aBiotechnology.
650 2 4 _aGene Expression.
650 2 4 _aNucleic Acid Chemistry.
650 2 4 _aCell Biology.
650 2 4 _aAnalytical Chemistry.
700 1 _aTan, Weihong.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642391088
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-39109-5
912 _aZDB-2-CMS
999 _c98392
_d98392