000 03980nam a22004695i 4500
001 978-3-642-36871-4
003 DE-He213
005 20140220082906.0
007 cr nn 008mamaa
008 130419s2013 gw | s |||| 0|eng d
020 _a9783642368714
_9978-3-642-36871-4
024 7 _a10.1007/978-3-642-36871-4
_2doi
050 4 _aQR355-502
072 7 _aMMFM
_2bicssc
072 7 _aMED052000
_2bisacsh
082 0 4 _a616.9101
_223
100 1 _aRicht, Jürgen A.
_eeditor.
245 1 0 _aSwine Influenza
_h[electronic resource] /
_cedited by Jürgen A. Richt, Richard J. Webby.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2013.
300 _aX, 303 p. 26 illus., 17 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v370
505 0 _aPreface -- Overview of influenza viruses -- History of swine influenza -- Genetics, evolution and the zoonotic capacity of European swine influenza virus.- History of swine influenza virus -- Clinicopathological features of swine influenza.- Diagnostics and surveillance for swine influenza.- Contemporary epidemiology of North American lineage triple reassortant influenza A viruses in pigs -- History and epidemiology of swine influenza in Europe.- Swine influenza viruses: an Asian perspective -- Swine influenza virus vaccines - to change, or not to change: that's the question.- Swine influenza virus infections in man -- Interspecies transmission of influenza A viruses between swine and poultry -- The 2009 pandemic influenza virus: Where did it come from, where is it now, and where is it going? - Pandemic influenza  A H1N1 in swine and other animals -- Therapeutics against influenza -- Subject index.  .
520 _aThe central role which swine have played in the ecology of influenza is set out in this book in 15 chapters within a comprehensive international framework. The result is a ‘One Health’ perspective on the role of swine influenza viruses (SIVs) at the animal-human-environmental interface.  The epidemiology of swine influenza worldwide is now of exceptional importance with the pig potentially acting as a “mixing vessel” where both avian and human influenza viruses can undergo genetic reassortment resulting in the creation of novel viruses that can cross species barriers. The genetic features of SIVs with either limited or efficient spread to and between humans are largely unknown, but the host range barrier between human and swine highlights the fact that adaptation of a virus in one mammalian host does not necessarily mean that it is well adapted to replication in another. However, in 2012 zoonotic transmission of SIV (both H3N2 and H1N2 subtypes) containing the matrix gene from the 2009 pandemic H1N1 virus was reported. These strains appeared to be able to spread more easily from pigs to people than other influenza viruses of swine. Therefore, this multifaceted book has assumed greater significance. Clearly, the dynamic nature and the national and international complexity of SIVs pose challenges for the swine industry as a recurring respiratory disease in swine, and also for public health as a continuing source of zoonotic infection. 
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aMedical virology.
650 1 4 _aBiomedicine.
650 2 4 _aVirology.
650 2 4 _aImmunology.
700 1 _aWebby, Richard J.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642368707
830 0 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v370
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-36871-4
912 _aZDB-2-SBL
999 _c97979
_d97979