000 03642nam a22004815i 4500
001 978-3-642-36002-2
003 DE-He213
005 20140220082902.0
007 cr nn 008mamaa
008 130321s2013 gw | s |||| 0|eng d
020 _a9783642360022
_9978-3-642-36002-2
024 7 _a10.1007/978-3-642-36002-2
_2doi
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.6
_223
100 1 _aKeeley, Fred W.
_eeditor.
245 1 0 _aEvolution of Extracellular Matrix
_h[electronic resource] /
_cedited by Fred W. Keeley, Robert P. Mecham.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2013.
300 _aX, 290 p. 50 illus., 23 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aBiology of Extracellular Matrix,
_x0887-3224
505 0 _aJosephine C. Adams: Extracellular Matrix Evolution: An Overview -- Hiroshi Wada: Domain Shuffling and the Evolution of Vertebrate Extracellular Matrix -- Jean-Yves Exposito, Claire Lethias: Invertebrate and Vertebrate Collagens -- Fred. W. Keeley: The Evolution of Elastin -- Sacha Jensen, David Yadin, Ian Robertson, Penny Handford: Evolutionary Insights into Fibrillin Structure and Function in the Extracellular Matrix -- Fernando Segade: Molecular Evolution of the Microfibril-associated Proteins: The Fibulins and the MAGPs -- Cristina A. Baratta, Theodore J. Brown, Fahd Al-Dhalaan, Maurice J. Ringuette: Evolution and Function of SPARC and Tenascins: Matricellular Counter-adhesive Glycoproteins with Pleotropic Effects on Angiogenesis and Tissue Fibrosis -- David D. Roberts, William A. Frazier: Thrompospondins and their Receptors: Evolving Functions -- Mark S. Johnson, Jarmo Käpylä, Konstantin Denissiouk, Tomi Airenne, Bhanupratap Singh Chouhan, Jyrki Heino: Evolution of Cell Adhesion to Extracellular Matrix.
520 _aThe evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function.  This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.
650 0 _aLife sciences.
650 0 _aCytology.
650 0 _aEvolution (Biology).
650 1 4 _aLife Sciences.
650 2 4 _aCell Biology.
650 2 4 _aEvolutionary Biology.
650 2 4 _aCell Physiology.
700 1 _aMecham, Robert P.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642360015
830 0 _aBiology of Extracellular Matrix,
_x0887-3224
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-36002-2
912 _aZDB-2-SBL
999 _c97766
_d97766