000			03101nam a22005295i 4500
001			978-3-642-35935-4
003			DE-He213
005			20140220082902.0
007			cr nn 008mamaa
008			130321s2013 gw | s |||| 0|eng d
020			_a9783642359354 _9978-3-642-35935-4
024	7		_a10.1007/978-3-642-35935-4 _2doi
050		4	_aQH491
072		7	_aPSC _2bicssc
072		7	_aSCI072000 _2bisacsh
082	0	4	_a571.8 _223
100	1		_aDeSimone, Douglas W. _eeditor.
245	1	0	_aExtracellular Matrix in Development _h[electronic resource] / _cedited by Douglas W. DeSimone, Robert P. Mecham.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2013.
300			_aX, 253 p. 41 illus., 37 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aBiology of Extracellular Matrix, _x0887-3224
505	0		_aPart I Informational signals in extracellular matrix and matrix influences on cell movement in the developing embryo -- Part II Extracellular matrix-direct morphogenesis, growth factor signaling, and maintenance of the stem cell niche -- Part III Model organisms and the lexicon of developmental signals associated with the extracellular matrix.
520			_aCells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.
650		0	_aLife sciences.
650		0	_aCytokines.
650		0	_aCytology.
650		0	_aStem cells.
650		0	_aDevelopmental biology.
650	1	4	_aLife Sciences.
650	2	4	_aDevelopmental Biology.
650	2	4	_aCell Biology.
650	2	4	_aRegenerative Medicine/Tissue Engineering.
650	2	4	_aCytokines and Growth Factors.
650	2	4	_aStem Cells.
700	1		_aMecham, Robert P. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783642359347
830		0	_aBiology of Extracellular Matrix, _x0887-3224
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-642-35935-4
912			_aZDB-2-SBL
999			_c97754 _d97754