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001 978-3-642-35810-4
003 DE-He213
005 20140220082901.0
007 cr nn 008mamaa
008 130327s2013 gw | s |||| 0|eng d
020 _a9783642358104
_9978-3-642-35810-4
024 7 _a10.1007/978-3-642-35810-4
_2doi
050 4 _aQP34-38
072 7 _aMFG
_2bicssc
072 7 _aMED075000
_2bisacsh
082 0 4 _a612
_223
100 1 _aHeber-Katz, Ellen.
_eeditor.
245 1 0 _aNew Perspectives in Regeneration
_h[electronic resource] /
_cedited by Ellen Heber-Katz, David L. Stocum.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2013.
300 _aX, 281 p. 40 illus., 34 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v367
505 0 _aMechanisms of Vessel Regression: Toward an Understanding of the Resolution of Angiogenesis -- Wound Healing in Mammals and Amphibians: Toward Limb Regeneration in Mammals -- Cellular Plasticity During Vertebrate Appendage Regeneration -- Cell Signaling Pathways in Vertebrate Lens Regeneration -- Regenerative Medicine: Challenges and Perspectives for Successful Therapies -- Employing the Biology of Successful Fracture Repair to Heal Critical Size Bone Defects -- Muscle Repair and Regeneration:  Stem Cells, Scaffolds, and the Contributions of Skeletal Muscle to Amphibian Limb Regeneration -- Neural Regeneration -- Teleost Fish as a Model System to Study Successful Regeneration of the Central Nervous System -- Epigenetics and Regeneration -- Cell Cycle Regulation and Regeneration.     .
520 _aRegeneration, the homeostatic ability to maintain tissue structure in the face of normal cell turnover or loss of tissue damaged by trauma or disease, is an essential  developmental process that continues throughout life. As recently as a decade ago, any serious discussion of the possibility of regeneration becoming a practical medical tool in the near future had the air of science fiction or over-optimistic speculation. The term “regenerative medicine” was certainly on many lips but few actually expected to soon see it applied in a clinical setting. A tidal wave of discovery has changed that and investigating the cellular mechanisms of natural regeneration has become one of the hottest topics in developmental biology and biomedicine in general.   Many researchers entering the field find that the regeneration literature is still quite diffuse perhaps owing to the disparate biological systems that have been the object of study including hydra, planaria, newts, axolotls and more recently several mouse strains. The volume editors believe that an attempt to organize or systematize the literature is long overdue. In this volume, respected experts highlight the latest findings in vertebrate (including mammals) wound healing and regeneration. They present eleven reviews that cover a wide range of topics, from wound repair and its relationship to regeneration, through systems including lenticular, neural, and musculoskeletal tissues and limbs, to epigenetics and the role of the cell cycle. Nuclear reprogramming and cellular plasticity, which open the door for potential regenerative medical therapies for injury and degenerative disease, are recurring themes throughout the book. We are all now part of the regeneration revolution.
650 0 _aMedicine.
650 0 _aHuman genetics.
650 0 _aHuman physiology.
650 0 _aNeurosciences.
650 0 _aDevelopmental biology.
650 1 4 _aBiomedicine.
650 2 4 _aHuman Physiology.
650 2 4 _aHuman Genetics.
650 2 4 _aNeurosciences.
650 2 4 _aRegenerative Medicine/Tissue Engineering.
650 2 4 _aDevelopmental Biology.
700 1 _aStocum, David L.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642358098
830 0 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v367
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-35810-4
912 _aZDB-2-SBL
999 _c97722
_d97722