000 03962nam a22005655i 4500
001 978-3-642-32329-4
003 DE-He213
005 20140220082852.0
007 cr nn 008mamaa
008 120928s2013 gw | s |||| 0|eng d
020 _a9783642323294
_9978-3-642-32329-4
024 7 _a10.1007/978-3-642-32329-4
_2doi
050 4 _aTP155-156
072 7 _aTDC
_2bicssc
072 7 _aSCI013060
_2bisacsh
082 0 4 _a660
_223
100 1 _aPiletsky, Sergey A.
_eeditor.
245 1 0 _aDesigning Receptors for the Next Generation of Biosensors
_h[electronic resource] /
_cedited by Sergey A. Piletsky, Michael J. Whitcombe.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2013.
300 _aXII, 264 p. 133 illus., 70 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Series on Chemical Sensors and Biosensors, Methods and Applications,
_x1612-7617 ;
_v12
505 0 _aMultichannel Sensors Based on Biphenyl and Cyclohexane Conformational Changes -- Learning from Proteins and Drugs: Receptors that Mimic Biomedically Important Binding Motifs -- Molecular Recognition of Nucleotides -- Molecular Recognition of Oligopeptides and Protein Surfaces -- Antimicrobial Peptides for Detection and Diagnostic Assays -- Plastic Antibodies -- Computational Approaches in the Design of Synthetic Receptors -- MIP Sensors on the Way to Real-World Applications -- Molecularly Imprinted Au Nanoparticle Composites for Selective Sensing Applications -- Design and Development of in vivo Sensor Systems: The Long and Tortured Road to a Self-Contained, Implantable Glucose Sensor for Diabetes Management -- Evolving Trends in Transition Metal-Modified Receptor Design and Function.
520 _aDespite achievements in the application of enzymes, antibodies and biological receptors to diagnostics and sensing, the last two decades have also witnessed the emergence of a number of alternative technologies based on synthetic chemistry. This volume shows how synthetic receptors can be designed with characteristics that make them attractive alternatives to biological molecules in the sensory and diagnostics fields, with contributions from leading experts in the area. Subjects covered include synthetic receptors for a range of biomolecules, the use of antimicrobial peptides for the detection of pathogenic microorganisms, the development of molecularly imprinted polymer (MIP) nanoparticles, the in silico design of MIPs and MIP-based sensors, and two chapters examining the development of sensors from an industrial point of view. The particular focus of all chapters is on practical aspects, either in the development process or the applications of the synthesized materials. This book will serve as an important reference work for business leaders and technology experts in the sensors and diagnostics sector.
650 0 _aChemistry.
650 0 _aAnalytical biochemistry.
650 0 _aBioorganic chemistry.
650 0 _aChemical engineering.
650 0 _aBiochemistry.
650 0 _aBiomedical engineering.
650 0 _aBiomaterials.
650 1 4 _aChemistry.
650 2 4 _aIndustrial Chemistry/Chemical Engineering.
650 2 4 _aAnalytical Chemistry.
650 2 4 _aMedicinal Chemistry.
650 2 4 _aBioorganic Chemistry.
650 2 4 _aBiomedical Engineering.
650 2 4 _aBiomaterials.
700 1 _aWhitcombe, Michael J.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642323287
830 0 _aSpringer Series on Chemical Sensors and Biosensors, Methods and Applications,
_x1612-7617 ;
_v12
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-32329-4
912 _aZDB-2-CMS
999 _c97224
_d97224