000 02510nam a22004935i 4500
001 978-1-4614-6111-1
003 DE-He213
005 20140220082823.0
007 cr nn 008mamaa
008 130321s2013 xxu| s |||| 0|eng d
020 _a9781461461111
_9978-1-4614-6111-1
024 7 _a10.1007/978-1-4614-6111-1
_2doi
050 4 _aQR180-189.5
072 7 _aMJCM
_2bicssc
072 7 _aMED044000
_2bisacsh
082 0 4 _a616.079
_223
100 1 _aDivangahi, Maziar.
_eeditor.
245 1 4 _aThe New Paradigm of Immunity to Tuberculosis
_h[electronic resource] /
_cedited by Maziar Divangahi.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2013.
300 _aVI, 292 p. 20 illus., 17 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v783
520 _aThis book illustrates the intimate relationship between alveolar macrophages and Mycobacterium tuberculosis (M.tb.), and the former’s role in both innate and adaptive immunity against M.tb. It covers research done over the last decade. It also explores the role of macrophage death following infection with M.tb. in determining whether successful immunity is stimulated, or whether clinical disease develops; furthermore, the function of host lipid mediators in macrophage death modality are addressed. The book also illustrates how the balance between prostaglandins and lipoxins determines whether infected macrophages undergo apoptosis or necrosis, which is the ultimate factor in the outcome of infection. Finally, it is a synthesis of the authors’ recent studies and the studies of others to offer a new understanding of immunity to tuberculosis.
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aMonoclonal antibodies.
650 0 _aMicrobiology.
650 0 _aVaccines.
650 1 4 _aBiomedicine.
650 2 4 _aImmunology.
650 2 4 _aMedical Microbiology.
650 2 4 _aAntibodies.
650 2 4 _aVaccine.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461461104
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v783
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-6111-1
912 _aZDB-2-SBL
999 _c95588
_d95588