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001 978-1-4614-5857-9
003 DE-He213
005 20140220082822.0
007 cr nn 008mamaa
008 130330s2013 xxu| s |||| 0|eng d
020 _a9781461458579
_9978-1-4614-5857-9
024 7 _a10.1007/978-1-4614-5857-9
_2doi
050 4 _aQP34-38
072 7 _aMFG
_2bicssc
072 7 _aMED075000
_2bisacsh
082 0 4 _a612
_223
100 1 _aMehta, Jawahar L.
_eeditor.
245 1 0 _aBiochemical Basis and Therapeutic Implications of Angiogenesis
_h[electronic resource] /
_cedited by Jawahar L. Mehta, Naranjan S. Dhalla.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2013.
300 _aXVIII, 532 p. 66 illus., 52 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Biochemistry in Health and Disease ;
_v6
505 0 _aPart A: Molecular Mechanisms of Angiogenesis -- Endothelial Growth Factor Receptors in Angiogenesis -- Role of Transforming Growth Factor Beta in Angiogenesis -- Role of Cytokines in Angiogenesis: Turning it On and Off -- Neuropeptides in Angiogenesis -- The Role of Integrins in Angiogenesis -- Regulation of Angiogenesis by Hypoxia-inducible Factors -- Role of Mast Cells in Angiogenesis -- Vascular Stem Cells in Regulation of Angiogenesis -- Toll-like Receptor-linked Signal Transduction in Angiogenesis -- The Role of Sex Steroids in Angiogenesis -- Biochemical Mechanisms of Exercise-induced Angiogenesis -- Part B: Pathophysiological Aspects of Angiogenesis -- Angiogenesis in Atherosclerosis: An Overview -- Role of Serotonin in Angiogenesis in Diabetes -- Brain Angiogenesis after Stroke -- Angiogenesis in Myocardial Ischemia -- Adipose Tissue-derived Mesenchymal Stem Cell and Angiogenesis in Ischemic Heart Disease -- Trials of Angiogenesis Therapy in Patients with ischemic Heart Disease -- Angiogenesis in Cancer -- Potential Mechanisms Linking Oxidized LDL to Susceptibility to Cancer -- Role of Genetic Polymorphisms in the Angiogenesis Pathway and Non-small Cell Lung Cancer Tumor Behavior -- Part C: Pharmacology and Therapy of Angiogenesis -- Angiogenesis and Arteriogenesis Factors: Their Role in the Treatment of Cancer and Arterial Regeneration -- Physiological Roles and Therapeutic Implications of Hepatocyte Growth Factor for Angiogenesis -- Harnessing Endothelial Progenitor Cells for Therapeutic Angiogenesis -- Microarray and MiRs in Angiogenesis -- MicroRNA and Cardiovascular Disorders, with a Focus on Angiogenesis -- An Overview of Angiogenesis Inhibitors from Natural Sources -- Index.
520 _aAngiogenesis plays a key role in human physiology and pathophysiology. While necessary for tissue growth and development, uncontrolled angiogenesis plays a role in the progression of certain tumors as well as atherosclerosis. Lack of angiogenesis may be the basis of myocardial ischemia and stroke. Knowledge on the mechanisms of angiogenesis is growing very rapidly, and may lead to important drugs for therapy of a variety of clinical disorders. Experts from around the world have contributed a vast array of data on different aspects of angiogenesis in this volume edited by Professors Mehta and Dhalla. This information will be of immense help to basic scientists, clinicians and those involved in drug development.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aHuman physiology.
650 0 _aCardiology.
650 0 _aCell receptors.
650 0 _aStem cells.
650 1 4 _aBiomedicine.
650 2 4 _aHuman Physiology.
650 2 4 _aCardiology.
650 2 4 _aCancer Research.
650 2 4 _aReceptors.
650 2 4 _aMolecular Medicine.
650 2 4 _aStem Cells.
700 1 _aDhalla, Naranjan S.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461458562
830 0 _aAdvances in Biochemistry in Health and Disease ;
_v6
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-5857-9
912 _aZDB-2-SBL
999 _c95520
_d95520