| 000 | 02592nam a22004455i 4500 | ||
|---|---|---|---|
| 001 | 978-3-7091-0687-7 | ||
| 003 | DE-He213 | ||
| 005 | 20140220082524.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 130913s2014 au | s |||| 0|eng d | ||
| 020 |
_a9783709106877 _9978-3-7091-0687-7 |
||
| 024 | 7 |
_a10.1007/978-3-7091-0687-7 _2doi |
|
| 050 | 4 | _aRC346-429.2 | |
| 072 | 7 |
_aMJN _2bicssc |
|
| 072 | 7 |
_aMED056000 _2bisacsh |
|
| 082 | 0 | 4 |
_a616.8 _223 |
| 100 | 1 |
_aWenning, Gregor K. _eeditor. |
|
| 245 | 1 | 0 |
_aMultiple System Atrophy _h[electronic resource] / _cedited by Gregor K. Wenning, Alessandra Fanciulli. |
| 264 | 1 |
_aVienna : _bSpringer Vienna : _bImprint: Springer, _c2014. |
|
| 300 |
_aXVI, 198 p. 33 illus., 20 illus. in color. _bonline resource. |
||
| 336 |
_atext _btxt _2rdacontent |
||
| 337 |
_acomputer _bc _2rdamedia |
||
| 338 |
_aonline resource _bcr _2rdacarrier |
||
| 347 |
_atext file _bPDF _2rda |
||
| 505 | 0 | _a1. Historical Review -- 2. Epidemiology -- 3. Neuropathology -- 4. Etiopathogenesis -- 5. Animal Models -- 6. Clinical Presentation -- 7. Clinical diagnostic Criteria -- 8. Natural History -- 9. Investigations -- 10. Tratment. | |
| 520 | _aThis textbook provides a comprehensive monography on multiple system atrophy (MSA), a rare and fatal neurodegenerative disorder that presents with autonomic failure and either parkinsonism (MSA-P) or cerebellar ataxia (MSA-C).The underlying neuropathology of MSA is characterized by striatonigral degeneration (SND), olivopontocerebellar atrophy (OPCA) and unique oligodendroglial cytoplasmic alpha-synuclein inclusions. MSA is therefore classified among the alpha-synucleinopathies such as Parkinson`s disease, pure autonomic failure and dementia with Lewy bodies. Over the last decade there have been important advances in early diagnosis, pathogenesis research and clinical trial activity. The monography will cover the entire spectrum ranging from molecular and genetic work to symptomatic and interventional therapies. The book is written for movement disorder clinicians and basic neuroscientists interested in degenerative movement disorders. | ||
| 650 | 0 | _aMedicine. | |
| 650 | 0 | _aNeurosciences. | |
| 650 | 0 | _aNeurology. | |
| 650 | 1 | 4 | _aMedicine & Public Health. |
| 650 | 2 | 4 | _aNeurology. |
| 650 | 2 | 4 | _aNeurosciences. |
| 700 | 1 |
_aFanciulli, Alessandra. _eeditor. |
|
| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9783709106860 |
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-7091-0687-7 |
| 912 | _aZDB-2-SME | ||
| 999 |
_c93647 _d93647 |
||