000			03662nam a22004695i 4500
001			978-3-642-40829-8
003			DE-He213
005			20140220082521.0
007			cr nn 008mamaa
008			131126s2014 gw | s |||| 0|eng d
020			_a9783642408298 _9978-3-642-40829-8
024	7		_a10.1007/978-3-642-40829-8 _2doi
050		4	_aQR355-502
072		7	_aMMFM _2bicssc
072		7	_aMED052000 _2bisacsh
082	0	4	_a616.9101 _223
100	1		_aPalmer, Kenneth. _eeditor.
245	1	0	_aPlant Viral Vectors _h[electronic resource] / _cedited by Kenneth Palmer, Yuri Gleba.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2014.
300			_aX, 194 p. 33 illus., 19 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aCurrent Topics in Microbiology and Immunology, _x0070-217X ; _v375
505	0		_aPreface -- A personal history of virus-based vector construction by William O. Dawson -- Virus-derived ssDNA vectors for the expression of foreign proteins in plants by Edward P. Rybicki and Darrin P. Martin -- Plant Viral Epitope Display Systems for Vaccine Development by Denis Leclerc -- Applications of plant viruses in bionanotechnology by George P. Lomonossoff and David J. Evans -- Milestones in the development and applications of plant virus vector as gene silencing platforms -- by Christophe Lacomme -- Emerging Antibody-based Products by Kevin J. Whaley, Josh Morton, Steve Hume, Ernie Hiatt, Barry Bratcher, Victor Klimyuk, Andrew Hiatt, Michael Pauly, and Larry Zeitlin -- Production of Recombinant Antigens and Antibodies in Nicotiana benthamiana Using ‘magnifection’ Technology: GMP-Compliant Facilities for Small-and Large-Scale Manufacturing by Victor Klimyuk, Gregory Pogue, Stefan Herz, John Butler, and Hugh Haydon -- Plant viral vectors for delivery by Agrobacterium by Yuri Y. Gleba, Daniel Tusé and Anatoli Giritch -- Subject index.
520			_aIn this volume, the authors provide an excellent overview of how far the plant viral vector field has come. This discipline is no longer exclusively the domain of academics − there is a small, but growing number of small biotechnology companies that exploit plant viruses as a platform for commercial innovation in crop improvement, industrial product manufacturing, and human and veterinary health care.  The authors, who work in the plant viral “vectorology” field, have Bill Dawson to thank in some way for their scientific pedigree, and they are honored that he contributed the opening chapter of this volume with the history of plant virus vector development: “A vector is not a virus; it is a device designed to perform a specific function.” Other contributors have provided fascinating reviews of how plant viral vectors have been adapted to serve specific functions, from plant gene function discovery to nanotechnology, providing infinitely scalable manufacturing systems valuable for human therapeutics.
650		0	_aMedicine.
650		0	_aVaccines.
650		0	_aMedical virology.
650	1	4	_aBiomedicine.
650	2	4	_aVirology.
650	2	4	_aVaccine.
700	1		_aGleba, Yuri. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783642408281
830		0	_aCurrent Topics in Microbiology and Immunology, _x0070-217X ; _v375
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-642-40829-8
912			_aZDB-2-SBL
999			_c93454 _d93454