000			03452nam a22004455i 4500
001			978-3-642-40034-6
003			DE-He213
005			20140220082520.0
007			cr nn 008mamaa
008			131203s2014 gw | s |||| 0|eng d
020			_a9783642400346 _9978-3-642-40034-6
024	7		_a10.1007/978-3-642-40034-6 _2doi
050		4	_aRE1-994
072		7	_aMJQ _2bicssc
072		7	_aMED063000 _2bisacsh
082	0	4	_a617.7 _223
100	1		_aGirach, Aniz. _eeditor.
245	1	0	_aDiseases of the Vitreo-Macular Interface _h[electronic resource] / _cedited by Aniz Girach, Marc D. Smet.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2014.
300			_aIX, 122 p. 40 illus., 20 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aEssentials in Ophthalmology, _x1612-3212
505	0		_aIntroduction: Unmet Medical Need -- Epidemiology of Vitreo-Macular Interface Diseases -- Anatomy and Physiology of the Vitreo-Macular Interface -- Pathophysiology of the Ageing Vitreous -- Pathophysiology of Vitreo-Macular Traction -- Imaging of the Vitreo-Macular Interface -- Clinical Manifestations of Vitreo-Macular Interface Disease -- Vitreo-Macular Traction and Age-Related Macular Degeneration -- Treatment Paradigm for Vitreo-Macular Interface Diseases -- Pharmacologic Vitreolysis - Experimental Evidence -- Pharmacologic Vitreolysis - Clinical Trial Data -- Pharmacologic Vitreolysis - New Perspectives, Future Directions.
520			_aDisease of the vitreo-macular interface is characterized by vitreo-macular adhesion (VMA), which can lead to abnormal forces on the retina termed vitreo-macular traction (VMT). This combination of VMA and VMT can itself cause impairment of vision and is implicated in a variety of disorders, including wet age-related macular degeneration, diabetic retinopathy, macular edema, and macular hole. Vitreo-macular interface disease has recently begun to receive more attention owing in part to the advent of new imaging techniques that allow more accurate diagnosis and in part to advances in treatment.  This clinically oriented book is the first to be devoted wholly to the diagnosis and treatment of vitreo-macular interface disease. World-renowned experts in the field discuss epidemiologic, anatomic, and physiologic aspects, document the findings obtained with newer imaging techniques, such as spectral domain optical coherence tomography, describe the treatment options, and report on the results of preclinical and clinical trials, including some previously unpublished findings. This book will prove invaluable for ophthalmologists as we advance toward a future in which treatments of diseases such as age-related macular degeneration and diabetic retinopathy will likely require adjunctive therapy to tackle VMA/VMT concurrently.
650		0	_aMedicine.
650		0	_aOphthalmology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aOphthalmology.
700	1		_aSmet, Marc D. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783642400339
830		0	_aEssentials in Ophthalmology, _x1612-3212
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-642-40034-6
912			_aZDB-2-SME
999			_c93382 _d93382