000 04706nam a22005175i 4500
001 978-1-4614-8690-9
003 DE-He213
005 20140220082502.0
007 cr nn 008mamaa
008 131104s2014 xxu| s |||| 0|eng d
020 _a9781461486909
_9978-1-4614-8690-9
024 7 _a10.1007/978-1-4614-8690-9
_2doi
050 4 _aRC321-580
072 7 _aPSAN
_2bicssc
072 7 _aMED057000
_2bisacsh
082 0 4 _a612.8
_223
100 1 _aLo, Eng H.
_eeditor.
245 1 0 _aVascular Mechanisms in CNS Trauma
_h[electronic resource] /
_cedited by Eng H. Lo, Josephine Lok, MingMing Ning, Michael J. Whalen.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2014.
300 _aXX, 518 p. 45 illus., 28 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Series in Translational Stroke Research ;
_v5
505 0 _aCNS Barriers in Neurotrauma -- Mechanisms of Cerebral Edema Leading to Early Seizures after Traumatic Brain Injury -- Human Cerebral Blood Flow and Traumatic Brain Injury -- Gliovascular Targets in Traumatic CNS Injury -- Neurovascular Responses to Traumatic Brain Injury -- The Effects of Intravascular Coagulation and Microthrombosis on Cerebral Perfusion after Brain Trauma -- Barriers to Drug Delivery for Brain Trauma -- Angiogenesis and Functional Recovery after Traumatic Brain Injury -- Vascular Mechanisms in Spinal Cord Injury -- Neurovascular Mechanisms of Ischemia Tolerance Against Brain Injury -- Stem Cells for Neurovascular Repair in CNS Trauma -- Vascular Actions of Hypothermia in Brain Trauma -- Vascular Responses in Rodent Models of Traumatic Brain Injury -- SAH Models: Review, New Modification, and Prospective -- Age and Sex Differences In Hemodynamics In a Large Animal Model of Brain Trauma -- Neutrophils as Determinants of Vascular Stability in the Injured Spinal Cord -- Blood Biomarkers for Acute CNS Insults: Traumatic Brain Injury and Stroke -- Biomaterials for CNS Injury -- Isolated Blood Vessel Models for Studying Trauma -- Managing Edema and Intracranial Pressure in the Intensive Care Unit -- Surgical Management of Traumatic Brain Edema -- Optimizing Hemodynamics in the Clinical Setting -- Cerebrovascular Autoregulation and Monitoring of Cerebrovascular Reactivity -- Cerebrovascular Responses after Pediatric Traumatic Brain Injury -- Subdural Hematoma in Non-Accidental Head Injury -- Blood Genomics after Brain Ischemia, Hemorrhage, and Trauma -- Molecular Biomarkers in Neurocritical Care – The Next Frontier -- Bedside Monitoring of Vascular Mechanisms in CNS Trauma: The use of Near Infra-red Spectroscopy (NIRS) and Transcranial Doppler (TCD) -- In vivo MRI and MRS of Cerebrovascular Function following Traumatic Brain Injury.
520 _aVascular Mechanisms in CNS Trauma focuses on the vascular aspects of brain and spinal cord trauma.  Twenty nine chapters are arranged in three sections—Molecular Mechanisms; Experimental Models and Methods; and Clinical Challenges and Opportunities.  The first section addresses topics in the basic biology of brain and spinal cord trauma, ranging from the pathophysiology of cerebral endothelial cells and gliovascular interactions to the role of stem cells in neurovascular repair. The second section covers experimental methods in rodent and in large animal models of CNS injury, as well as the use of biomaterials and biomarkers in studying the mechanisms of tissue response. The third section deals with clinical issues in the monitoring and treatment of the patient with traumatic injury of the brain and spinal cord. Contributors to the book include an integrated mix of basic scientists and clinicians from diverse institutions. By presenting salient issues in CNS trauma from a vascular perspective, this book should make a unique contribution to the understanding of traumatic brain and spinal cord injury.
650 0 _aMedicine.
650 0 _aNeurosciences.
650 0 _aNeurology.
650 0 _aNeurobiology.
650 1 4 _aBiomedicine.
650 2 4 _aNeurosciences.
650 2 4 _aNeurology.
650 2 4 _aNeurobiology.
700 1 _aLok, Josephine.
_eeditor.
700 1 _aNing, MingMing.
_eeditor.
700 1 _aWhalen, Michael J.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461486893
830 0 _aSpringer Series in Translational Stroke Research ;
_v5
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-8690-9
912 _aZDB-2-SME
999 _c92224
_d92224