000			03510cam a2200493Ki 4500
001			9780429200151
003			FlBoTFG
005			20220509193123.0
006			m o d
007			cr |||||||||||
008			190826s2020 si a fob 000 0 eng d
040			_aOCoLC-P _beng _erda _cOCoLC-P
020			_a9780429578069 _q(e-book)
020			_a0429578067 _q(e-book)
020			_a9780429200151 _q(electronic bk.)
020			_a0429200153 _q(electronic bk.)
020			_a9780429573842 _q(electronic bk. : Mobipocket)
020			_a0429573847 _q(electronic bk. : Mobipocket)
020			_a9780429575952 _q(electronic bk. : EPUB)
020			_a0429575955 _q(electronic bk. : EPUB)
020			_z9789814800358 (hbk.)
035			_a(OCoLC)1191064451
035			_a(OCoLC-P)1191064451
050		4	_aQP620
072		7	_aSCI _x010000 _2bisacsh
072		7	_aTBN _2bicssc
082	0	4	_a547.7 _223
245	0	0	_aSpherical nucleic acids : _bthe foundation for crystal engineering with DNA and digital probe and drug design / _cedited by Chad A. Mirkin.
264		1	_aSingapore : _bJenny Stanford Publishing, _c[2020]
300			_a1 online resource : _billustrations
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
520			_aSpherical nucleic acids (SNAs) comprise a nanoparticle core and a densely packed and highly oriented nucleic acid shell, typically DNA or RNA. They have novel architecture-dependent properties that distinguish them from all other forms of nucleic acids and make them useful in materials synthesis, catalysis, diagnostics, therapeutics, and optics/plasmonics. This book covers over two decades of Dr. Mirkin's research on SNAs and their anisotropic analogues, including synthesis and fundamental properties, and applications in colloidal crystallization, adaptive matter, and nanomedicine, spanning extra- and intracellular diagnostics, gene regulation, and immunomodulation. It is a reprint volume that compiles 101 key papers from high-impact journals in this research area published by the Mirkin Group at Northwestern University, Illinois, USA, within the International Institute for Nanotechnology, and collaborators. Volume 1 provides an overview and a historical framework of engineering matter from DNA-modified constructs and discusses the enabling features of nucleic acid-functionalized nanomaterials. Volume 2 covers design rules for colloidal crystallization, building blocks for crystal engineering, and DNA and RNA as programmable bonds. Volume 3 discusses colloidal crystallization processes and routes to hierarchical assembly, dynamic nanoparticle superlattices, surface-based and template-confined colloidal crystallization, optics and plasmonics with nanoparticle superlattices, and postsynthetic modification and catalysis with nanoparticle superlattices. Volume 4 covers diagnostic modalities, and intracellular therapeutic and diagnostic schemes based upon nucleic acid-functionalized nanomaterials.
588			_aOCLC-licensed vendor bibliographic record.
650		0	_aNucleic acids.
650		0	_aRNA _xSynthesis.
650		0	_aDNA _xSynthesis.
650		0	_aNanochemistry.
650		0	_aDrug development.
650		7	_aSCIENCE / Biotechnology _2bisacsh
700	1		_aMirkin, Chad A., _eeditor.
856	4	0	_3Taylor & Francis _uhttps://www.taylorfrancis.com/books/9780429200151
856	4	2	_3OCLC metadata license agreement _uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf
999			_c130300 _d130300