000			03541nam a22005175i 4500
001			978-90-481-8833-8
003			DE-He213
005			20140220084602.0
007			cr nn 008mamaa
008			100726s2010 ne | s |||| 0|eng d
020			_a9789048188338 _9978-90-481-8833-8
024	7		_a10.1007/978-90-481-8833-8 _2doi
050		4	_aRC261-271
072		7	_aMJCL _2bicssc
072		7	_aMED062000 _2bisacsh
082	0	4	_a614.5999 _223
100	1		_aBeauchemin, Nicole. _eeditor.
245	1	0	_aMetastasis of Colorectal Cancer _h[electronic resource] / _cedited by Nicole Beauchemin, Jacques Huot.
264		1	_aDordrecht : _bSpringer Netherlands : _bImprint: Springer, _c2010.
300			_aXVI, 416 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aCancer Metastasis - Biology and Treatment, _x1568-2102 ; _v14
505	0		_aThe Metastatic Process: An Overview -- Physiopathology of Colorectal Metastasis -- The Genetics of Colorectal Cancer -- Epigenetics of Colorectal Cancer -- Cancer-Initiating Cells in Colorectal Cancer -- Epithelial-Mesenchymal Transition in Colorectal Cancer -- Cell Adhesion Molecules in Colon Cancer Metastasis -- Epithelial Cell Signalling in Colorectal Cancer Metastasis -- Angiogenesis and Lymphangiogenesis in Colon Cancer Metastasis -- Role of the Host Inflammatory Response in Colon Carcinoma Initiation, Progression and Liver Metastasis -- Molecular Prognostic Markers in Colon Cancer -- The Sentinel Lymph Node and Staging of Colorectal Cancer -- Treatment of Colorectal Cancer -- Diagnosis and Treatment of Rectal Cancer -- Future Directions.
520			_aColorectal cancer is the third most common cancer worldwide, and in many parts of the western world, it is the second leading cause of cancer-related deaths. This book covers colon cancer metastasis from the most fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, cell adhesion, natures of liver metastasis, angiogenesis and lymphangiogenesis, inflammatory response, prognostic markers, sentinel node and staging, and finally diagnosis and treatment. Each chapter has been contributed by leaders in the field. A key feature is that it connects with a large readership including students, fundamentalists and clinicians. Another specific feature of the book is that the chapters are written in a didactic and illustrative fashion. These characteristics coupled with the choice of the topics and authors, makes this book a reference in the field. It represents an essential acquisition for medical libraries, clinicians as well as medical and graduate students.
650		0	_aMedicine.
650		0	_aOncology.
650		0	_aMonoclonal antibodies.
650		0	_aPathology.
650	1	4	_aBiomedicine.
650	2	4	_aCancer Research.
650	2	4	_aOncology.
650	2	4	_aMolecular Medicine.
650	2	4	_aAntibodies.
650	2	4	_aPathology.
700	1		_aHuot, Jacques. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9789048188321
830		0	_aCancer Metastasis - Biology and Treatment, _x1568-2102 ; _v14
856	4	0	_uhttp://dx.doi.org/10.1007/978-90-481-8833-8
912			_aZDB-2-SBL
999			_c113554 _d113554