000 04088nam a22004935i 4500
001 978-90-481-2632-3
003 DE-He213
005 20140220084555.0
007 cr nn 008mamaa
008 100301s2010 ne | s |||| 0|eng d
020 _a9789048126323
_9978-90-481-2632-3
024 7 _a10.1007/978-90-481-2632-3
_2doi
050 4 _aR-RZ
072 7 _aMBGR
_2bicssc
072 7 _aMED000000
_2bisacsh
082 0 4 _a610
_223
100 1 _aMarijnissen, J.C.
_eeditor.
245 1 0 _aNanoparticles in medicine and environment
_h[electronic resource] :
_bInhalation and health effects /
_cedited by J.C. Marijnissen, Leon Gradon.
264 1 _aDordrecht :
_bSpringer Netherlands,
_c2010.
300 _bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aThe Origin and Production of Nanoparticles in Environment and Industry -- Characterization of Combustion and Engine Exhaust Particles -- Medicine Nanoparticle Production by EHDA -- Electrospray and Its Medical Applications -- Generation of Nanoparticles from Vapours in Case of Exhaust Filtration -- Measurement and Characterization of Aerosol Nanoparticles -- Inhalation and Deposition of Nanoparticles: Fundamentals, Phenomenology and Practical Aspects -- Dosimetry of Inhaled Nanoparticles -- Particles of Biomedical Relevance and Their Interactions: A Classical and Quantum Mechanistic Approach to a Theoretical Description -- Health Effects of Nanoparticles (Inhalation) from Medical Point of View/Type of Diseases -- Effects of Cigarette Smoke and Diesel Exhaust on the Innate Immune Function of the Airway Epithelium -- The Potential Harmful and Beneficial Effects of Nanoparticles in Children -- Targeting Drugs to the Lungs – The Example of Insulin -- Protection of the Respiratory System Against Nanoparticles Inhalation -- Overview and Discussion.
520 _aA huge effort is put into the science of nanoparticles and their production. In many cases it is unavoidable that nanoparticles are released into the environment, either during the production processes or during the use of a product made from these particles. It is also realized that combustion processes like traffic and power plants release nanoparticles into the atmosphere. However it is not known how nanoparticles interact with the human body, especially upon inhalation. At the same time research activities are devoted to understand how nano-sized medicine particles can be used to administer medicines via inhalation. In any case it is absolutely necessary to know how the nanoparticles interfere with the inhalation system, how they deposit and affect on the human system. Three main themes are discussed: Nanoparticle sources and production Nanoparticle inhalation and deposition Toxicological and medical consequences of nanoparticles Each theme is covered comprehensively, starting at nano-quantum effects up to technical and medical applications such as measuring equipment and inhalation instrumentation. This book brings together all sub-disciplines in the field related to aerosol nanoparticles. Each chapter is written by a world expert, giving the state of the art information and challenging open questions. The last chapter summarizes in an interdisciplinary way what is already known and what still is ahead of us.
650 0 _aMedicine.
650 0 _aToxicology.
650 0 _aEngineering.
650 0 _aEnvironmental Medicine.
650 1 4 _aBiomedicine.
650 2 4 _aBiomedicine general.
650 2 4 _aNanotechnology and Microengineering.
650 2 4 _aPublic Health/Gesundheitswesen.
650 2 4 _aEnvironmental Health.
650 2 4 _aPharmacology/Toxicology.
700 1 _aGradon, Leon.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789048126316
856 4 0 _uhttp://dx.doi.org/10.1007/978-90-481-2632-3
912 _aZDB-2-SBL
999 _c113207
_d113207