000 02732nam a22005175i 4500
001 978-3-642-13893-5
003 DE-He213
005 20140220084540.0
007 cr nn 008mamaa
008 101013s2010 gw | s |||| 0|eng d
020 _a9783642138935
_9978-3-642-13893-5
024 7 _a10.1007/978-3-642-13893-5
_2doi
050 4 _aR856-857
072 7 _aMQW
_2bicssc
072 7 _aTEC009000
_2bisacsh
082 0 4 _a610.28
_223
100 1 _aRoy, Krishnendu.
_eeditor.
245 1 0 _aBiomaterials as Stem Cell Niche
_h[electronic resource] /
_cedited by Krishnendu Roy.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2010.
300 _aVIII, 309 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aStudies in Mechanobiology, Tissue Engineering and Biomaterials,
_x1868-2006 ;
_v2
520 _aRecent developments in stem cell biology have opened new directions in cell therapy. This book provides the state-of-the-art developments in using biomaterials as artificial niches for engineering stem cells, both for the purpose of better understanding their biology under 3D biomimetic conditions as well as for developing new strategies for efficient long term maintenance and directed differentiation of stem cells into various therapeutic lineages. Animal and human stem cells of both embryonic and adult origin are discussed with applications ranging from nerve regeneration, orthopedics, cardiovascular therapy, blood cell generation and cancer therapy. Both synthetic and natural biomaterials are reviewed with emphasis on how material-stem cell interactions direct specific signaling pathways and ultimately modulate the cell fate. This book is valuable for biomaterial scientists, tissue engineers, clinicians as well as stem cell biologists involved in basic research and applications of adult and embryonic stem cells.
650 0 _aEngineering.
650 0 _aHuman genetics.
650 0 _aBiochemistry.
650 0 _aStem cells.
650 0 _aBiomedical engineering.
650 0 _aBiomaterials.
650 1 4 _aEngineering.
650 2 4 _aBiomedical Engineering.
650 2 4 _aStem Cells.
650 2 4 _aBiomaterials.
650 2 4 _aHuman Genetics.
650 2 4 _aMedical Biochemistry.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642138928
830 0 _aStudies in Mechanobiology, Tissue Engineering and Biomaterials,
_x1868-2006 ;
_v2
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-13893-5
912 _aZDB-2-ENG
999 _c112360
_d112360