| 000 | 03101nam a22004815i 4500 | ||
|---|---|---|---|
| 001 | 978-1-4419-6741-1 | ||
| 003 | DE-He213 | ||
| 005 | 20140220084510.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 110110s2010 xxu| s |||| 0|eng d | ||
| 020 |
_a9781441967411 _9978-1-4419-6741-1 |
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| 024 | 7 |
_a10.1007/978-1-4419-6741-1 _2doi |
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| 050 | 4 | _aQH506 | |
| 072 | 7 |
_aMBGR _2bicssc |
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_aPSD _2bicssc |
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_aSCI049000 _2bisacsh |
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| 072 | 7 |
_aMED067000 _2bisacsh |
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| 082 | 0 | 4 |
_a611.01816 _223 |
| 100 | 1 |
_aChalfant, Charles. _eeditor. |
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| 245 | 1 | 0 |
_aSphingolipids as Signaling and Regulatory Molecules _h[electronic resource] / _cedited by Charles Chalfant, Maurizio Del Poeta. |
| 264 | 1 |
_aNew York, NY : _bSpringer New York, _c2010. |
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| 300 |
_aXXVI, 287p. 47 illus., 2 illus. in color. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
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| 490 | 1 |
_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v688 |
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| 505 | 0 | _aAn Overview of Sphingolipid Metabolism: From Synthesis to Breakdown -- Sphingolipid Transport -- Sphingolipid Analysis by High Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS) -- Ceramide Synthases: Roles in Cell Physiology and Signaling -- Tales and Mysteries of the Enigmatic Sphingomyelin Synthase Family -- Ceramide in Stress Response -- Animal Models for Studying the Pathophysiology of Ceramide -- Ceramide-1-Phosphate in Cell Survival and Inflammatory Signaling -- Ceramide-1-Phosphate in Phagocytosis and Calcium Homeostasis -- Extracellular and Intracellular Actions of Sphingosine-1-Phosphate -- Glucosylceramide in Humans -- Gangliosides as Regulators of Cell Membrane Organization and Functions -- Cancer Treatment Strategies Targeting Sphingolipid Metabolism -- Therapeutic Strategies for Diabetes and Complications: A Role for Sphingolipids? -- Roles for Sphingolipids in Saccharomyces cerevisiae -- Sphingolipid Signaling in Fungal Pathogens -- Sphingolipids in Parasitic Protozoa -- Biosynthesis of Sphingolipids in Plants (and Some of Their Functions) -- Computational Analysis of Sphingolipid Pathway Systems. | |
| 520 | _aThis book attempts to analyze the latest discoveries in sphingolipid biology and how the alteration of their metabolism leads to altered signaling events and to the development of pathobiological disorders, such as cancer, cardiovascular diseases, asthma, diabetes, inflammation and infectious diseases. | ||
| 650 | 0 | _aMedicine. | |
| 650 | 0 | _aToxicology. | |
| 650 | 1 | 4 | _aBiomedicine. |
| 650 | 2 | 4 | _aMolecular Medicine. |
| 650 | 2 | 4 | _aPharmacology/Toxicology. |
| 700 | 1 |
_aPoeta, Maurizio Del. _eeditor. |
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| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9781441967404 |
| 830 | 0 |
_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v688 |
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| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-1-4419-6741-1 |
| 912 | _aZDB-2-SBL | ||
| 999 |
_c110687 _d110687 |
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