| 000 | 02774nam a22004335i 4500 | ||
|---|---|---|---|
| 001 | 978-1-4419-6706-0 | ||
| 003 | DE-He213 | ||
| 005 | 20140220084510.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 110110s2010 xxu| s |||| 0|eng d | ||
| 020 |
_a9781441967060 _9978-1-4419-6706-0 |
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| 024 | 7 |
_a10.1007/978-1-4419-6706-0 _2doi |
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| 050 | 4 | _aR-RZ | |
| 072 | 7 |
_aMBGR _2bicssc |
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| 072 | 7 |
_aMED000000 _2bisacsh |
|
| 082 | 0 | 4 |
_a610 _223 |
| 100 | 1 |
_aHetz, Claudio. _eeditor. |
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| 245 | 1 | 0 |
_aBCL-2 Protein Family _h[electronic resource] : _bEssential Regulators of Cell Death / _cedited by Claudio Hetz. |
| 264 | 1 |
_aNew York, NY : _bSpringer New York, _c2010. |
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| 300 |
_aXVIII, 142p. 27 illus. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
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| 490 | 1 |
_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v687 |
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| 505 | 0 | _aHomeostatic Functions of BCL-2 Proteins beyond Apoptosis -- Alternative Functions of the BCL-2 Protein Family at the Endoplasmic Reticulum -- BH3-Only Proteins and Their Effects on Cancer -- Endoplasmic Reticulum Stress and BCL-2 Family Members -- Targeting Survival Pathways in Lymphoma -- The Interplay between BCL-2 Family Proteins and Mitochondrial Morphology in the Regulation of Apoptosis -- Noncanonical Functions of BCL-2 Proteins in the Nervous System -- Mitochondria on Guard: Role of Mitochondrial Fusion and Fission in the Regulation of Apoptosis. | |
| 520 | _aIn this book, scientists pioneering the field have compiled a series of focused chapters to highlight the relevance of the BCL‑2 family of proteins in apoptosis, physiology and disease. An important focus of this volume is considering the potential TH ERA PEUT IC benefits of targeting apoptosis pathways in the context of human disease. Readers interested in understanding how a cell handles stress and the consequences of dysregulation of this process for human disease will find this book very valuable. It attempts to describe a fascinating area of research where physiology and biomedicine converge at different levels, revealing a trip from the molecular regulation of apoptosis to the impact of this process to the physiology of a whole organism. | ||
| 650 | 0 | _aMedicine. | |
| 650 | 1 | 4 | _aBiomedicine. |
| 650 | 2 | 4 | _aBiomedicine general. |
| 650 | 2 | 4 | _aMolecular Medicine. |
| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9781441967053 |
| 830 | 0 |
_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v687 |
|
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-1-4419-6706-0 |
| 912 | _aZDB-2-SBL | ||
| 999 |
_c110683 _d110683 |
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