000			03042nam a22004695i 4500
001			978-1-4419-6673-5
003			DE-He213
005			20140220084510.0
007			cr nn 008mamaa
008			110110s2010 xxu| s |||| 0|eng d
020			_a9781441966735 _9978-1-4419-6673-5
024	7		_a10.1007/978-1-4419-6673-5 _2doi
050		4	_aRB155-155.8
050		4	_aQH431
072		7	_aMFN _2bicssc
072		7	_aMED107000 _2bisacsh
072		7	_aSCI029000 _2bisacsh
082	0	4	_a611.01816 _223
100	1		_aDeutsch, Jean S. _eeditor.
245	1	0	_aHox Genes _h[electronic resource] : _bStudies from the 20th to the 21st Century / _cedited by Jean S. Deutsch.
264		1	_aNew York, NY : _bSpringer New York, _c2010.
300			_aXXIV, 166p. 34 illus., 2 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v689
505	0		_aMechanisms of Activity -- Regulation of Hox Activity: Insights from Protein Motifs -- Cis-Regulation in the Drosophila Bithorax Complex -- Maintenance of Hox Gene Expression Patterns -- Control of Vertebrate Hox Clusters by Remote and Global Cis-Acting Regulatory Sequences -- Evolution of Hox Genes and Complexes -- The Early Evolution of Hox Genes: A Battle of Belief? -- Evolution of Hox Complexes -- The Nematode Story: Hox Gene Loss and Rapid Evolution -- Are the Deuterostome Posterior Hox Genes a Fast-Evolving Class? -- Biological Function -- Hox Genes and the Body Plans of Chelicerates and Pycnogonids -- Hox3/zen and the Evolution of Extraembryonic Epithelia in Insects -- Hox Genes and Brain Development in Drosophila -- Homeosis and Beyond. What Is the Function of the Hox Genes?.
520			_aThe purpose of this book is to argue, and to convince those who may not agree, that the Hox genes are indeed so important that their study will not end with the 20th century. The book is divided into three major sections. The first section covers aspects of the regulation of Hox gene expression and the structure and function of the now justifiably well-known homeobox. The second section offers insights and discussions of the sometimes contentious issues of the origin and evolution of the aforementioned Hox complexes. In the third and last section the role of the resident loci in the specification of body plans and meristic identity of the arthropods is presented.
650		0	_aMedicine.
650		0	_aMedical genetics.
650	1	4	_aBiomedicine.
650	2	4	_aGene Function.
650	2	4	_aBiomedicine general.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781441966728
830		0	_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v689
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4419-6673-5
912			_aZDB-2-SBL
999			_c110676 _d110676