000			03495nam a22004455i 4500
001			978-1-4419-6658-2
003			DE-He213
005			20140220084510.0
007			cr nn 008mamaa
008			130531s2010 xxu| s |||| 0|eng d
020			_a9781441966582 _9978-1-4419-6658-2
024	7		_a10.1007/978-1-4419-6658-2 _2doi
050		4	_aRC681-688.2
072		7	_aMJD _2bicssc
072		7	_aMED010000 _2bisacsh
082	0	4	_a616.12 _223
100	1		_aSigg, Daniel C. _eeditor.
245	1	0	_aCardiac Electrophysiology Methods and Models _h[electronic resource] / _cedited by Daniel C. Sigg, Paul A. Iaizzo, Yong-Fu Xiao, Bin He.
264		1	_aBoston, MA : _bSpringer US : _bImprint: Springer, _c2010.
300			_aXIV, 475p. 172 illus., 93 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aClinical Cardiac Electrophysiology: An Overview of Its Evolution -- Clinical Cardiac Electrophysiology: An Overview of Its Evolution -- Overview -- Basic Cardiac Electrophysiology: Excitable Membranes -- Cardiac Action Potentials, Ion Channels, and Gap Junctions -- Anatomy and Physiology of the Cardiac Conduction System -- The Electrocardiogram and Clinical Cardiac Electrophysiology -- Methods and Models -- Principles of Electrophysiological In Vitro Measurements -- Cardiac Cellular Electrophysiological Modeling -- Computer Modeling of Electrical Activation: From Cellular Dynamics to the Whole Heart -- Detection and Measurement of Cardiac Ion Channels -- Cell Culture Models and Methods -- Isolated Tissue Models -- Isolated Heart Models -- Small Animal Models for Arrhythmia Studies -- Use of Large Animal Models for Cardiac Electrophysiology Studies -- Optical Mapping and Calcium Imaging -- Electrophysiology of Single Cardiomyocytes: Patch Clamp and Other Recording Methods -- Invasive Electroanatomical Mapping and Navigation -- Cardiac Electrophysiological Imaging: Solving the Inverse Problem of Electrocardiography -- Traditional Electrophysiological Mapping -- Multi-channel System for Analysis of Cardiac Rhythmicity and Conductivity In Vitro -- Cardiac CT/MRI Imaging for Electrophysiology -- Putting It All Together -- to Translational Research -- Clinical Perspective: Electrophysiology in the Young and Patients with Congenital Heart Disease.
520			_aBiomedical, pharmaceutical and medical personnel are interested in studying aspects of arrhythmias at a basic, translational and applied level. The overall understanding of the molecular basis of disease has dramatically increased, as well as the number of available and emerging molecular, pharmacological and device treatment based therapies. Cardiac Electrophysiology Methods and Models will review key research methods and protocols in cardiac electrophysiology with a focus on advantages, pitfalls, practical implementation and collaborative cross-functional research.
650		0	_aMedicine.
650		0	_aCardiology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aCardiology.
700	1		_aIaizzo, Paul A. _eeditor.
700	1		_aXiao, Yong-Fu. _eeditor.
700	1		_aHe, Bin. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781441966575
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4419-6658-2
912			_aZDB-2-SME
999			_c110673 _d110673