000 05154nam a22005295i 4500
001 978-1-4419-6603-2
003 DE-He213
005 20140220084510.0
007 cr nn 008mamaa
008 130531s2010 xxu| s |||| 0|eng d
020 _a9781441966032
_9978-1-4419-6603-2
024 7 _a10.1007/978-1-4419-6603-2
_2doi
050 4 _aRC254-282
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a616.994
_223
100 1 _aRodriguez-Bigas, Miguel A.
_eeditor.
245 1 0 _aHereditary Colorectal Cancer
_h[electronic resource] /
_cedited by Miguel A. Rodriguez-Bigas, Raul Cutait, Patrick M. Lynch, Ian Tomlinson, Hans F.A. Vasen.
264 1 _aBoston, MA :
_bSpringer US :
_bImprint: Springer,
_c2010.
300 _aXVIII, 630 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aM.D. Anderson Solid Tumor Oncology Series ;
_v5
505 0 _aHistory -- History: Familial Adenomatous Polyposis -- Historical Aspects of Lynch Syndrome -- Basic Sciences and Genetics -- Molecular Genetics of Familial Adenomatous Polyposis -- DNA Mismatch Repair -- Basic Sciences and Genetics: Hamartomatous Polyposis -- Hyperplastic Polyposis Syndrome: Colorectal Cancer Predisposition -- MUTYH-Associated Polyposis -- Polymorphic Variation and Risk of Colorectal Cancer -- Pathology -- The Pathologist and the Phenotype of Hereditary Colorectal Cancer -- Clinical Science: Familial Adenomatous Polyposis -- Genotype Phenotype Correlation in Familial Adenomatous Polyposis -- Surgery for Familial Adenomatous Polyposis -- Duodenal Adenomas in Familial Adenomatous Polyposis -- FAP-Associated Desmoid Tumours -- Attenuated Familial Adenomatous Polyposis: Diagnosis, Management, and Future Prognosis -- Clinical Science: Hereditary Nonpolyposis Colorectal Cancer -- An Overview of the Lynch Syndrome (Hereditary Non-polyposis Colorectal Cancer) -- Surgical Management in Lynch Syndrome -- Extracolonic Tumors -- Surveillance -- Clinical Science: MYH Associated Polyposis -- MUTYH-Associated Polyposis -- Clinical Science: Hamartomatous Polyposis -- Peutz–Jeghers Syndrome -- Clinical Aspects of Juvenile Polyposis -- Hereditary Mixed Polyposis Syndrome and Multiple Adenoma Patients -- Clinical Science: Hyperplastics Polyposis -- Hyperplastic Polyposis -- Genetic Counseling -- Genetic Counseling Overview -- Across Culture and Health Systems: Europe -- Across Culture and Health Systems: Asia (Hong Kong) -- Across Culture and Health Systems: Asia (Japan) -- Across Culture and Health Systems: Africa -- Across Culture and Health Systems: Argentina -- Genetic Counselling Across Culture and Health Systems: Australia -- Across Culture and Health Systems: Korea -- Across Culture and Health Systems: America -- Psychosocial Aspects of Hereditary Colorectal Cancer -- Psychological Impact of Genetic Counseling and Testing for Hereditary Colorectal Cancers -- Chemoprevention -- Chemoprevention for Inherited Colorectal Cancer -- Registries -- Registries -- Erratum -- Erratumto: Chapter 22: Hereditary Mixed Polyposis Syndrome and Multiple Adenoma Patients.
520 _aEarly detection of colorectal cancers is a significant and relatively recent achievement. Persons who carry genetic mutations linked to hereditary colorectal cancer make up 20% of the patient population. With the advent of molecular genetics and the description of hereditary colorectal cancer syndromes, clinicians and genetic counselors are able to use genetic predisposition testing as an effective and important way to identify patients and families affected by inherited colorectal cancer syndromes. Hereditary Colorectal Cancer is a comprehensive collection that documents not only Familial Adenomatous Polyposis and the Lynch syndrome, but also less understood syndromes, including the Hamartomatous Polyposis Syndromes and MutYH Associated Polyposis. Internationally recognized clinicians and researchers further delve into the evolution and potential of syndromes, genes and molecular alterations that have yet to be defined. Instrumental experts in this field of discovery were carefully selected by the section editors to create this premier reference work for clinicians, scientists and researchers confronted with the treatment and management of hereditary colorectal cancer.
650 0 _aMedicine.
650 0 _aGastroenterology.
650 0 _aOncology.
650 0 _aCancer
_xSurgery.
650 1 4 _aMedicine & Public Health.
650 2 4 _aOncology.
650 2 4 _aSurgical Oncology.
650 2 4 _aGastroenterology.
700 1 _aCutait, Raul.
_eeditor.
700 1 _aLynch, Patrick M.
_eeditor.
700 1 _aTomlinson, Ian.
_eeditor.
700 1 _aVasen, Hans F.A.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441966025
830 0 _aM.D. Anderson Solid Tumor Oncology Series ;
_v5
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-6603-2
912 _aZDB-2-SME
999 _c110666
_d110666