000 02893nam a22004215i 4500
001 978-1-4419-6354-3
003 DE-He213
005 20140220084509.0
007 cr nn 008mamaa
008 110110s2010 xxu| s |||| 0|eng d
020 _a9781441963543
_9978-1-4419-6354-3
024 7 _a10.1007/978-1-4419-6354-3
_2doi
050 4 _aR-RZ
072 7 _aMBGR
_2bicssc
072 7 _aMED000000
_2bisacsh
082 0 4 _a610
_223
100 1 _aCatania, Anna.
_eeditor.
245 1 0 _aMelanocortins: Multiple Actions and Therapeutic Potential
_h[electronic resource] /
_cedited by Anna Catania.
264 1 _aNew York, NY :
_bSpringer New York,
_c2010.
300 _aXX, 153 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v681
505 0 _aStructure-Activity Relationships (SAR) of Melanocortin and Agouti-Related (AGRP) Peptides -- Melanocortin Signalling Mechanisms -- Distribution and Function of Melanocortin Receptors within the Brain -- Drugs, Exercise, and the Melanocortin-4 Receptor— Different Means, Same Ends: Treating Obesity -- Melanocortins in Brain Inflammation: The Role of Melanocortin Receptor Subtypes -- Melanocortins and the Cholinergic Anti-Inflammatory Pathway -- Melanocortin Control of Cell Trafficking in Vascular Inflammation -- Terminal Signal: Anti-Inflammatory Effects of ?-Melanocyte-Stimulating Hormone Related Peptides Beyond the Pharmacophore -- Protective Effects of Melanocortins in Systemic Host Reactions -- Development of ?-Melanocortin Analogs for Melanoma Prevention and Targeting -- MSH Radiopeptides for Targeting Melanoma Metastases -- Applications of the Role of ?-MSH in Ocular Immune Privilege.
520 _aThis book represents the joint effort of an international group of scientists who are at the forefront of research in the field. The volume spans information on chemistry, pharmacology, distribution, and therapeutic potential of melanocortins. A recurrent theme of this volume is the role played by distinct melanocortin receptors in mediating melanocortin effects. Although these receptors have been identified and well-characterized, information in the book indicates that definite categorization of their expression and function in different conditions still needs major work.
650 0 _aMedicine.
650 1 4 _aBiomedicine.
650 2 4 _aBiomedicine general.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441963536
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v681
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-6354-3
912 _aZDB-2-SBL
999 _c110623
_d110623