000 02847nam a22004575i 4500
001 978-1-4419-6102-0
003 DE-He213
005 20140220084509.0
007 cr nn 008mamaa
008 100728s2010 xxu| s |||| 0|eng d
020 _a9781441961020
_9978-1-4419-6102-0
024 7 _a10.1007/978-1-4419-6102-0
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aRoth, Jack A.
_eeditor.
245 1 0 _aGene-Based Therapies for Cancer
_h[electronic resource] /
_cedited by Jack A. Roth.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2010.
300 _aXIV, 278 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Cancer Research
505 0 _aRNAi: A New Paradigm in Cancer Gene Therapy -- Gene-Based Therapy for Cancer: Brain Tumors -- Gene Therapy of Prostate Cancer -- siRNA Versus shRNA for Personalized Cancer Therapy: Mechanisms and Applications -- Tumor Suppressor Gene Therapy -- Targeted Oncolytic Adenovirus for Human Cancer Therapy: Gene-Based Therapies for Cancer -- Gene Therapy for Malignant Pleural Mesothelioma -- Mesenchymal Stem/Stromal Cells as Cellular Vehicles for Tumor Targeting -- Retargeting Adenovirus for Cancer Gene Therapy -- Lentiviruses: Vectors for Cancer Gene Therapy -- Interleukin-24 Gene Therapy for Melanoma -- Herpes Simplex Virus 1 for Cancer Therapy -- Telomerase as a Target for Cancer Therapeutics -- Gene Therapy for Sarcoma.
520 _aCancer gene therapy is a novel therapy that targets the underlying genetic defects in the cancer cell. Progress in this field has been rapid and gene therapy promises to further extend personalized cancer treatment. In this volume leading experts have contributed their experience in developing gene therapies for a variety of cancers. Translational gene therapy approaches are emphasized. Chapters include discussions of specific gene delivery technologies as well as their application to various cancers with extensive discussions of ongoing clinical trials. This information should be useful to students, fellows, clinical investigators, and experienced scientists with an interest in this rapidly developing area.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aToxicology.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aPharmacology/Toxicology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441961013
830 0 _aCurrent Cancer Research
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-6102-0
912 _aZDB-2-SME
999 _c110586
_d110586