| 000 | 02581nam a22005295i 4500 | ||
|---|---|---|---|
| 001 | 978-94-007-0618-7 | ||
| 003 | DE-He213 | ||
| 005 | 20140220083830.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 110815s2011 ne | s |||| 0|eng d | ||
| 020 |
_a9789400706187 _9978-94-007-0618-7 |
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| 024 | 7 |
_a10.1007/978-94-007-0618-7 _2doi |
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| 050 | 4 | _aRC261-271 | |
| 072 | 7 |
_aMJCL _2bicssc |
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| 072 | 7 |
_aMED062000 _2bisacsh |
|
| 082 | 0 | 4 |
_a614.5999 _223 |
| 100 | 1 |
_aHayat, M.A. _eeditor. |
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| 245 | 1 | 0 |
_aTumors of the Central Nervous System, Volume 2 _h[electronic resource] : _bGliomas: Glioblastoma (Part 2) / _cedited by M.A. Hayat. |
| 264 | 1 |
_aDordrecht : _bSpringer Netherlands, _c2011. |
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| 300 |
_aXXII, 458 p. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
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| 490 | 1 |
_aTumors of the Central Nervous System ; _v2 |
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| 520 | _aAdvantages and limitations of biomarkers in gliomagenesis are described. Molecular subtypes of gliomas are detailed. The role played by TP53 gene mutation in the deadliest brain tumor, glioblastoma multiforme, is pointed out. The role of mutations of IDH1 and IDH2, and isocitrate dehydrogenases in malignant gliomas are presented. Metabolic differences in different regions of the glioma tumor are clarified. Various types of imaging modalities, including PET and SPECT, to diagnose gliomas in general and glioblastoma in particular in patients are explained in detail. Both low-grade and high-grade gliomas are discussed. Conventional as well as fluorescent-guided resection techniques for high-grade, recurrent malignant gliomas are detailed. Impact of resection extent on outcomes in patients with high-grade gliomas is clarified. The advantage of the use of intraoperative low-field MRI in glioma surgery is explained. | ||
| 650 | 0 | _aMedicine. | |
| 650 | 0 | _aOncology. | |
| 650 | 0 | _aRadiology, Medical. | |
| 650 | 0 | _aNeurosurgery. | |
| 650 | 0 | _aPathology. | |
| 650 | 0 | _aSurgery. | |
| 650 | 1 | 4 | _aBiomedicine. |
| 650 | 2 | 4 | _aCancer Research. |
| 650 | 2 | 4 | _aNeuroradiology. |
| 650 | 2 | 4 | _aNeurosurgery. |
| 650 | 2 | 4 | _aOncology. |
| 650 | 2 | 4 | _aPathology. |
| 650 | 2 | 4 | _aSurgery. |
| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9789400706170 |
| 830 | 0 |
_aTumors of the Central Nervous System ; _v2 |
|
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-94-007-0618-7 |
| 912 | _aZDB-2-SBL | ||
| 999 |
_c109335 _d109335 |
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