000 | 03108nam a22004695i 4500 | ||
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001 | 978-90-481-9495-7 | ||
003 | DE-He213 | ||
005 | 20140220083824.0 | ||
007 | cr nn 008mamaa | ||
008 | 101013s2011 ne | s |||| 0|eng d | ||
020 |
_a9789048194957 _9978-90-481-9495-7 |
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024 | 7 |
_a10.1007/978-90-481-9495-7 _2doi |
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050 | 4 | _aRC261-271 | |
072 | 7 |
_aMJCL _2bicssc |
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072 | 7 |
_aMED062000 _2bisacsh |
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082 | 0 | 4 |
_a614.5999 _223 |
100 | 1 |
_aSlevin, Mark. _eeditor. |
|
245 | 1 | 0 |
_aTherapeutic Angiogenesis for Vascular Diseases _h[electronic resource] : _bMolecular Mechanisms and Targeted Clinical Approaches for the Treatment of Angiogenic Disease / _cedited by Mark Slevin. |
264 | 1 |
_aDordrecht : _bSpringer Netherlands : _bImprint: Springer, _c2011. |
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300 |
_aXVI, 430p. 50 illus., 30 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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520 | _aAngiogenesis is the growth of new blood vessels and is a key process which occurs during pathological disease progression. Excessive and damaging angiogenesis occurs in diseases such as cancer, diabetic retinopathies, age-related macular degeneration and atherosclerosis. In other diseases such as stroke and myocardial infarction, insufficient or improper angiogenesis results in tissue loss and ultimately higher morbidity and mortality. In this book we will begin by providing the reader with an overview of the process of angiogenesis including normal embryological development of blood vessels. The following chapters will each focus on a key angiogenic disease incorporating current scientific knowledge concerning the causes of activation of the “angiogenic switch”, pathological consequences, current treatment options and future perspectives. Where appropriate, results from pre-clinical trials, novel imaging modalities and nanotechnological approaches will be incorporated into these sections. Finally, since it is now believed that the process of angiogenesis operated via different signalling mechanisms in different vascular beds, we will discuss our current understanding of this phenomenon. The target audience for this book would include researchers in all the basic sciences; post-graduate students at Universities and Institutes; pharmaceutical industries; clinicians working in vascular biology or tissue imaging; pathologists; neurologists; tumour biologists; ophthalmologists and cardiologists. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aOncology. | |
650 | 0 | _aHuman genetics. | |
650 | 0 | _aNeurosciences. | |
650 | 1 | 4 | _aBiomedicine. |
650 | 2 | 4 | _aCancer Research. |
650 | 2 | 4 | _aOncology. |
650 | 2 | 4 | _aMolecular Medicine. |
650 | 2 | 4 | _aNeurosciences. |
650 | 2 | 4 | _aHuman Genetics. |
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9789048194940 |
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-90-481-9495-7 |
912 | _aZDB-2-SBL | ||
999 |
_c109031 _d109031 |