| 000 | 03148nam a22004095i 4500 | ||
|---|---|---|---|
| 001 | 978-90-481-9349-3 | ||
| 003 | DE-He213 | ||
| 005 | 20140220083824.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 101013s2011 ne | s |||| 0|eng d | ||
| 020 |
_a9789048193493 _9978-90-481-9349-3 |
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| 024 | 7 |
_a10.1007/978-90-481-9349-3 _2doi |
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| 050 | 4 | _aR-RZ | |
| 072 | 7 |
_aMBGR _2bicssc |
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| 072 | 7 |
_aMED000000 _2bisacsh |
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| 082 | 0 | 4 |
_a610 _223 |
| 100 | 1 |
_aKhardori, Nancy. _eeditor. |
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| 245 | 1 | 0 |
_aBiomedical Aspects of Histamine _h[electronic resource] : _bCurrent Perspectives / _cedited by Nancy Khardori, Rahat Ali Khan, Trivendra Tripathi. |
| 264 | 1 |
_aDordrecht : _bSpringer Netherlands : _bImprint: Springer, _c2011. |
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| 300 |
_aXXXV, 350p. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
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| 520 | _aSince its identification by Sir Henry H. Dale a century ago, histamine has become one of the most important multifunctional biogenic amines in the field of biomedicine. The pharmacological effects of histamine are mediated through four types of membrane histamine receptors; H1R, H2R, H3R and H4R, which are all heptahelical G-protein-coupled receptors. It has been known to play the broadest spectrum of activities in various physiological and pathological conditions including cell proliferation, differentiation, hematopoiesis, embryonic development, regeneration, wound healing, aminergic neurotransmission and numerous brain functions, secretion of pituitary hormones, regulation of gastrointestinal and circulatory functions, cardiovascular system, as well as inflammatory reactions, modulation of the immune response, endocrine function and homeostasis, and other important areas. This book is a compendium of the current state of established and investigational literature on Histamine, its receptors and their Agonists and antagonists. It provides a comprehensive overview of histamine biology in the field of biochemistry, cell biology, molecular biology, immunology, allergy, neurobiology, pharmacology, microbiology and reproductive biology. The first section on Histamine biology and physiology leads into subsequent sections on enzymology, pharmacology, regulation of the immune system and cell proliferation and role in allergic and other diseases including acid peptic diseases, inflammatory diseases, autoimmune and cancer diseases, nervous system, reproductive functions and hematopoiesis. The compilation of chapters in the book presents the most recent advances in histamine research and bridges the basic and clinical aspects of histamine biology. | ||
| 650 | 0 | _aMedicine. | |
| 650 | 1 | 4 | _aBiomedicine. |
| 650 | 2 | 4 | _aBiomedicine general. |
| 700 | 1 |
_aKhan, Rahat Ali. _eeditor. |
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| 700 | 1 |
_aTripathi, Trivendra. _eeditor. |
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| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9789048193486 |
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-90-481-9349-3 |
| 912 | _aZDB-2-SBL | ||
| 999 |
_c109017 _d109017 |
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