000			02917nam a22005295i 4500
001			978-4-431-92691-7
003			DE-He213
005			20140220083821.0
007			cr nn 008mamaa
008			110530s2011 ja | s |||| 0|eng d
020			_a9784431926917 _9978-4-431-92691-7
024	7		_a10.1007/978-4-431-92691-7 _2doi
050		4	_aQL1-991
072		7	_aPSVL _2bicssc
072		7	_aSCI070000 _2bisacsh
072		7	_aMED067000 _2bisacsh
082	0	4	_a616.027 _223
100	1		_aNaruse, Kiyoshi. _eeditor.
245	1	0	_aMedaka _h[electronic resource] : _bA Model for Organogenesis, Human Disease, and Evolution / _cedited by Kiyoshi Naruse, Minoru Tanaka, Hiroyuki Takeda.
264		1	_aTokyo : _bSpringer Japan : _bImprint: Springer, _c2011.
300			_aXVIII, 386p. 65 illus. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
520			_aOryzias latipes, known as medaka, is a model organism from East Asia. Breeding of this small, egg-laying freshwater teleost fish has long been popular among hobbyists in Japan. Now, as biological science has entered the genome era, the medaka provides significant advantages that make it one of the most valuable vertebrate models: a large collection of spontaneous mutants collected over a century, the presence of highly polymorphic inbred lines established over decades, and a recently completed genome sequence. This book is the first comprehensive monograph to cover a variety of medaka research. It opens with a historical view of medaka, followed by a series of research topics in the four major areas where the medaka is increasingly important: genomics, genetics, and resources; organogenesis and disease models; germ cells, sex determination, and reproduction; and evolution. Readers will find state-of-the-art information on medaka genetics and genomics such as the first isolation of active transposons in vertebrates, the influence of chromatin structure on sequence variation, fine QTL analysis, and versatile mutants as human disease models.
650		0	_aLife sciences.
650		0	_aDevelopmental biology.
650		0	_aEvolution (Biology).
650		0	_aAnimal genetics.
650		0	_aTransgenic organisms.
650		0	_aLaboratory animals.
650	1	4	_aLife Sciences.
650	2	4	_aAnimal Models.
650	2	4	_aDevelopmental Biology.
650	2	4	_aEvolutionary Biology.
650	2	4	_aTransgenics.
650	2	4	_aAnimal Genetics and Genomics.
700	1		_aTanaka, Minoru. _eeditor.
700	1		_aTakeda, Hiroyuki. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9784431926900
856	4	0	_uhttp://dx.doi.org/10.1007/978-4-431-92691-7
912			_aZDB-2-SBL
999			_c108816 _d108816