000 02719nam a22004815i 4500
001 978-4-431-89757-6
003 DE-He213
005 20140220083820.0
007 cr nn 008mamaa
008 101225s2011 ja | s |||| 0|eng d
020 _a9784431897576
_9978-4-431-89757-6
024 7 _a10.1007/978-4-431-89757-6
_2doi
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.6
_223
100 1 _aNoda, Masaki.
_eeditor.
245 1 0 _aMechanosensing Biology
_h[electronic resource] /
_cedited by Masaki Noda.
264 1 _aTokyo :
_bSpringer Japan :
_bImprint: Springer,
_c2011.
300 _aXIV, 218p. 49 illus., 2 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
520 _aMechanical stress is vital to the functioning of the body, especially for tissues such as bone, muscle, heart, and vessels. It is well known that astronauts and bedridden patients suffer muscle and bone loss from lack of use. Even the heart, in pumping blood, causes mechanical stress to itself and to vascular tissue. With the loss of mechanical stress, homeostasis becomes impaired and leads to pathological conditions such as osteopenia, muscle atrophy, and vascular tissue dysfunction. In elderly populations, such mechanical pathophysiology, as well as the mechanical activities of locomotor and cardiovascular systems, is important because skeletal and heart functions decline and cause diseases in other organs. In this monograph, mechanical stress is discussed by experts in the field with respect to molecular, cellular, and tissue aspects in relation to medicine. Covering topics such as gravity and tissues and disuse osteoporosis, the book provides the most up-to-date information on cutting-edge advancements in the field of mechanobiology and is a timely contribution to research into locomotor and circulatory diseases that are major problems in contemporary society.
650 0 _aLife sciences.
650 0 _aHuman physiology.
650 0 _aCytology.
650 0 _aAnimal Physiology.
650 0 _aBiomedical engineering.
650 1 4 _aLife Sciences.
650 2 4 _aCell Biology.
650 2 4 _aHuman Physiology.
650 2 4 _aAnimal Physiology.
650 2 4 _aBiophysics and Biological Physics.
650 2 4 _aBiomedical Engineering.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9784431897569
856 4 0 _uhttp://dx.doi.org/10.1007/978-4-431-89757-6
912 _aZDB-2-SBL
999 _c108815
_d108815