000 03480nam a22004935i 4500
001 978-4-431-53945-2
003 DE-He213
005 20140220083820.0
007 cr nn 008mamaa
008 110614s2011 ja | s |||| 0|eng d
020 _a9784431539452
_9978-4-431-53945-2
024 7 _a10.1007/978-4-431-53945-2
_2doi
050 4 _aRC321-580
072 7 _aPSAN
_2bicssc
072 7 _aMED057000
_2bisacsh
082 0 4 _a612.8
_223
100 1 _aSeki, Tatsunori.
_eeditor.
245 1 0 _aNeurogenesis in the Adult Brain II
_h[electronic resource] :
_bClinical Implications /
_cedited by Tatsunori Seki, Kazunobu Sawamoto, Jack M. Parent, Arturo Alvarez-Buylla.
264 1 _aTokyo :
_bSpringer Japan :
_bImprint: Springer,
_c2011.
300 _aXIV, 226p. 44 illus., 19 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _a1 Neurogenesis in Monkey and Human Adult Brain -- 2 Adult Neurogenesis in Parkinson’s Disease -- 3 Adult Neurogenesis in Epilepsy -- 4 Stress Disorders -- 5 Depression -- 6 Impaired Neurogenesis as a Risk Factor for Schizophrenia and Related Mental Diseases -- 7 Neurogenesis from Endogenous Neural Stem Cells After Stroke: A Future Therapeutic Target to Promote Functional Restoration? -- 8 Perspectives of “PUFA-GPR40 Signaling” Crucial for Adult Hippocampal Neurogenesis -- 9 Adult Neurogenesis and Neuronal Subtype Specification in the Neocortex -- 10 Culturing Adult Neural Stem Cells: Application to the Study of Neurodegenerative and Neuropsychiatric Pathology -- Index.
520 _aThe discovery of adult neurogenesis caused a paradigm shift in the neurosciences. For more than 100 years, it was believed that adult neurons do not regenerate. Joseph Altman and Fernando Nottebohm found proof to the contrary and changed the course of history. Their research, included here, provides the foundations of the field. Today, adult neurogenesis is a rapidly expanding discipline applicable to the study of brain development and diseases, learning and memory, aging, and neuropsychiatric disorders. With multiple authors, the 27 chapters of this book contain the latest work in two volumes. The first presents the basic biology of adult neurogenesis in non-mammalian vertebrates and in the mammalian hippocampus and olfactory bulb, and the second discusses clinical implications and delves into adult neurogenesis and brain injury as well as neurodegenerative and neuropsychiatric pathologies. With details of the anatomy, physiology, and molecular biology of the two neurogenic brain regions, this book provides indispensable knowledge for many areas of neuroscience and for experimental and clinical applications of adult neurogenesis to brain therapy.
650 0 _aMedicine.
650 0 _aNeurosciences.
650 0 _aNeurology.
650 0 _aCytology.
650 1 4 _aBiomedicine.
650 2 4 _aNeurosciences.
650 2 4 _aCell Biology.
650 2 4 _aNeurology.
700 1 _aSawamoto, Kazunobu.
_eeditor.
700 1 _aParent, Jack M.
_eeditor.
700 1 _aAlvarez-Buylla, Arturo.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9784431539445
856 4 0 _uhttp://dx.doi.org/10.1007/978-4-431-53945-2
912 _aZDB-2-SBL
999 _c108810
_d108810