000 04271nam a22005535i 4500
001 978-3-642-21230-7
003 DE-He213
005 20140220083803.0
007 cr nn 008mamaa
008 110829s2011 gw | s |||| 0|eng d
020 _a9783642212307
_9978-3-642-21230-7
024 7 _a10.1007/978-3-642-21230-7
_2doi
050 4 _aQP501-801
072 7 _aPSV
_2bicssc
072 7 _aPSB
_2bicssc
072 7 _aSCI007000
_2bisacsh
072 7 _aSCI070000
_2bisacsh
082 0 4 _a573.44
_223
100 1 _aMüller, Werner E. G.
_eeditor.
245 1 0 _aMolecular Biomineralization
_h[electronic resource] :
_bAquatic Organisms Forming Extraordinary Materials /
_cedited by Werner E. G. Müller.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2011.
300 _aXII, 404 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aProgress in Molecular and Subcellular Biology,
_x0079-6484 ;
_v52
505 0 _aMagnetite Biomineralization in Bacteria -- Maxi and Mini Ferritins: Minerals and Protein Nanocages -- Manganese Oxidation by Bacteria: Biogeochemical Aspects -- Molecular Biomineralization: Towards an Understanding of the Biogenic Origin of Polymetallic Nodules, Seamount Crusts and Hydrothermal Vents.- Molecular basis of bacterial calcium carbonate precipitation -- Principles of calcium-based biomineralization -- Molecular Aspects of Biomineralization of the Echinoderm Endoskeleton -- Echinoderms as blueprints for biocalcification: regulation of skeletogenic genes and matrices -- The unique invention of the siliceous sponges: their enzymatically made bio-silica skeleton -- Biosilica-based strategies for treatment of osteoporosis and other bone diseases -- Structure and function of matrix proteins and peptides in the biomineral formation in crustaceans -- Molecular Approaches to Understand Biomineralization of Shell Nacreous Layer -- Acidic shell proteins of the Mediterranean fan mussel Pinna nobili.
520 _aThe concept of ‘biomineralization’ signifies mineralization processes that take place in close association with organic molecules or matrices. The awareness that mineral formation can be guided by organic molecules notably contributed to the understanding of the formation of the inorganic skeletons of living organisms. Modern electron microscopic and spectroscopic analyses have successfully demonstrated the participation of biological systems in several mineralization processes, and prominent examples include the formation of bio-silica in diatoms and sponges. This insight has already made the application of recombinant technology for the production of valuable inorganic polymers, such as bio-silica, possible. This polymer can be formed by silicatein under conditions that cannot be matched by chemical means. Similarly, the efforts described in this book have elucidated that certain organisms, bacteria in deep-sea polymetallic nodules and coccoliths in seamount crusts, are involved in the deposition of marine minerals. Strategies have already been developed to utilize such microorganisms for the biosynthesis and bioleaching of marine deposits. Moreover, studies reveal that bio-polymers enhance the hydroxyapatite formation of bone-forming cells and alter the expression of important regulators of bone resorption, suggesting a potential for bone regeneration and treatment / prevention of osteoporosis.
650 0 _aLife sciences.
650 0 _aMedicine.
650 0 _aBiotechnology.
650 0 _aBiochemistry.
650 0 _aAquatic biology.
650 0 _aBiomaterials.
650 1 4 _aLife Sciences.
650 2 4 _aAnimal Biochemistry.
650 2 4 _aFreshwater & Marine Ecology.
650 2 4 _aBiomaterials.
650 2 4 _aBiotechnology.
650 2 4 _aMolecular Medicine.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642212291
830 0 _aProgress in Molecular and Subcellular Biology,
_x0079-6484 ;
_v52
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-21230-7
912 _aZDB-2-SBL
999 _c107930
_d107930