000 04358nam a22005295i 4500
001 978-3-642-18095-8
003 DE-He213
005 20140220083752.0
007 cr nn 008mamaa
008 110909s2011 gw | s |||| 0|eng d
020 _a9783642180958
_9978-3-642-18095-8
024 7 _a10.1007/978-3-642-18095-8
_2doi
050 4 _aR856-857
072 7 _aMQW
_2bicssc
072 7 _aTEC009000
_2bisacsh
082 0 4 _a610.28
_223
100 1 _aMcGloughlin, Tim.
_eeditor.
245 1 0 _aBiomechanics and Mechanobiology of Aneurysms
_h[electronic resource] /
_cedited by Tim McGloughlin.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2011.
300 _aXIV, 426 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aStudies in Mechanobiology, Tissue Engineering and Biomaterials,
_x1868-2006 ;
_v7
505 0 _aEpidemiology Aetiology and Pathophysiology -- Advanced medical imaging in aneurysm diagnostics Biomechanics and Pathobiology of Aortic Aneurysm -- Computer-Aided Diagnosis of Abdominal Aortic Aneurysms -- New diagnostic approaches to AAA and Mechanical behavior of AAA tissue -- Fluid mechanics in -- Biomechanical aspects of Abdominal Aortic Aneurysm (AAA) and its risk of rupture: Fluid Structure Interaction (FSI) studies -- Computational analysis of displacement forces acting on endografts used to treat aortic aneurysms -- Experimental modelling of aneurysm behavior -- Endovascular treatment of AAA and long term outcomes -- Thoracic aortic aneurysms, clinical assessment and treatment -- Cranial aneurysms clinical assessment and treatment options -- Modelling Cerebral Aneurysm Evolution -- Biomechanical considerations of animal models of aneurysm.
520 _aCardiovascular disease is the leading cause of morbidity and premature death of modern era medicine. It is estimated that approximately 81 million people in the United States (US) currently have one or more of the many forms of cardiovascular disease, resulting in 1 in every 2.8 deaths, or 900,000 deaths per year. 40% of all deaths in Europe are a result of cardiovascular disease in people under the age of 75.  Aneurysms form a significant portion of these cardiovascular related deaths and are defined as a permanent and irreversible localised dilation of a blood vessel greater than 50% of its normal diameter. Although aneurysms can form in any blood vessel, the more lethal aneurysms develop in the cranial arteries, and in the thoracic aorta and abdominal aorta. Frequently aneurysms are undetected and if left untreated may eventually expand until rupture with very high levels of morbidity and mortality. The biomechanics and mechanobiology of aneursymal diseases are not fully understood and this monograph aims to provide new insights into aneurysm aetiology and behavior based on the most recent biomechanics research related to this important topic. The contributors to this volume bring together a unique blend of expertise in experimental, computational and tissue biomechanics relating to aneurysm behavior and enable the reader to gain a fresh understanding of key factors influencing aneurysm behavior and treatment. Biological risk factors such as tobacco smoking, sex, age, hypertension, family history and mechanobiological risk factors such as aneurysm geometry and shape as well as mechanical properties of the diseased tissues are considered in detail as are many of the diagnostic and treatment options.
650 0 _aEngineering.
650 0 _aHuman physiology.
650 0 _aHeart
_xSurgery.
650 0 _aMaterials.
650 0 _aBiomedical engineering.
650 0 _aBiomaterials.
650 1 4 _aEngineering.
650 2 4 _aBiomedical Engineering.
650 2 4 _aBiomaterials.
650 2 4 _aHuman Physiology.
650 2 4 _aCardiac Surgery.
650 2 4 _aContinuum Mechanics and Mechanics of Materials.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642180941
830 0 _aStudies in Mechanobiology, Tissue Engineering and Biomaterials,
_x1868-2006 ;
_v7
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-18095-8
912 _aZDB-2-ENG
999 _c107370
_d107370