| 000 | 02700nam a22004575i 4500 | ||
|---|---|---|---|
| 001 | 978-1-4614-0040-0 | ||
| 003 | DE-He213 | ||
| 005 | 20140220083731.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 110823s2011 xxu| s |||| 0|eng d | ||
| 020 |
_a9781461400400 _9978-1-4614-0040-0 |
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| 024 | 7 |
_a10.1007/978-1-4614-0040-0 _2doi |
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| 050 | 4 | _aRC261-271 | |
| 072 | 7 |
_aMJCL _2bicssc |
|
| 072 | 7 |
_aMED062000 _2bisacsh |
|
| 082 | 0 | 4 |
_a614.5999 _223 |
| 100 | 1 |
_aZakhari, Samir. _eeditor. |
|
| 245 | 1 | 0 |
_aAlcohol and Cancer _h[electronic resource] / _cedited by Samir Zakhari, Vasilis Vasiliou, Q. Max Guo. |
| 264 | 1 |
_aNew York, NY : _bSpringer New York, _c2011. |
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| 300 |
_aXVI, 243p. 63 illus., 57 illus. in color. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
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| 505 | 0 | _aAlcohol as a Human Carcinogen -- Overview of Tumorigenesis -- Alcohol and Cancer Epidemiology -- Alcohol Metabolism and Its Implications for Cancer -- Epigenetics, Alcohol, and Cancer.- Alcohol, Cancer Genes, and Signaling Pathways.- Alcohol, Retinoic Acid, and Cancer -- Alcohol, Altered Protein Homeostasis, and Cancer -- Alcohol and the Inflammatory Function of Immune Cells in Cancer Development -- Immune Surveillance and Tumor Evasion -- Stem Cells and Alcohol-related Cancers -- Epilogue, Consensus Recommendations - Alcohol and Cancer. | |
| 520 | _aThe World Health Organization has identified chronic alcohol consumption as one of the top ten risk factors for worldwide burden of disease. The International Agency for Research on Cancer has identified alcohol as carcinogenic to humans, including cancers of the upper aerodigestive tract, colon, liver and breast. Alcohol’s actions may be direct e.g. effects on retinoic acid and one-carbon metabolism, or indirect, through metabolites such as acetaldehyde and reactive oxygen species or through various signaling pathways that influence cell cycle and apoptosis that may contribute to carcinogenesis. This volume reviews the state of the art in alcohol-related cancer research in ten chapters. | ||
| 650 | 0 | _aMedicine. | |
| 650 | 0 | _aOncology. | |
| 650 | 0 | _aToxicology. | |
| 650 | 1 | 4 | _aBiomedicine. |
| 650 | 2 | 4 | _aCancer Research. |
| 650 | 2 | 4 | _aPharmacology/Toxicology. |
| 700 | 1 |
_aVasiliou, Vasilis. _eeditor. |
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| 700 | 1 |
_aGuo, Q. Max. _eeditor. |
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| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9781461400394 |
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-1-4614-0040-0 |
| 912 | _aZDB-2-SBL | ||
| 999 |
_c106192 _d106192 |
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