000 03046nam a22004455i 4500
001 978-1-4419-8414-2
003 DE-He213
005 20140220083728.0
007 cr nn 008mamaa
008 110609s2011 xxu| s |||| 0|eng d
020 _a9781441984142
_9978-1-4419-8414-2
024 7 _a10.1007/978-1-4419-8414-2
_2doi
050 4 _aR-RZ
072 7 _aMBGR
_2bicssc
072 7 _aMED000000
_2bisacsh
082 0 4 _a610
_223
100 1 _aRobinson, Mark W.
_eeditor.
245 1 0 _aCysteine Proteases of Pathogenic Organisms
_h[electronic resource] /
_cedited by Mark W. Robinson, John P. Dalton.
264 1 _aBoston, MA :
_bSpringer US,
_c2011.
300 _aXIX, 226 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v712
505 0 _aPapa In‑Like Proteases Of Staphylococcus Aureus -- The Lysine‑Specific Gingipain Of Porphyromonas: Importance To Pathogenicity -- Falcipains And Other Cysteine Proteases Of Malaria Parasites -- Cathepsin Proteases In Toxoplasma Gondii -- Entamoeba Histolytica Cathepsin‑Like Enzymes -- Cysteine Peptidases Of Kinetoplastid Parasites -- Cruzain: The Path From Target Validation To The Clinic -- The Phylogeny, Structure And Function Of Trematode Cysteine Proteases, With Particular Emphasis On The Fasciola Hepatica Cathepsin L Family -- Cathepsins B1 And B2 Of Trichobilharzia Spp., Bird Schistosomes Causing Cercarial Dermatitis -- Proteases In Blood‑Feeding Nematodes And Their Potential As Vaccine Candidates -- Cysteine Proteases From Bloodfeeding Arthropod Ectoparasites -- How Pathogen‑Derived Cysteine Proteases Modulate Host Immune Responses -- Cystatins Of Parasitic Organisms.
520 _aCysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host immune responses. This book gives comprehensive coverage to all aspects of pathogen cysteine proteases and brings together numerous scientific advances which have been made over many years. Thus, the biochemistry, molecular biology and structure‑function relationships of these important pathogen enzymes are covered in detail. Written by leading researchers from Europe, Australia and North America, this book is essential reading for students and professionals interested in human medicine and infectious disease research.
650 0 _aMedicine.
650 1 4 _aBiomedicine.
650 2 4 _aBiomedicine general.
650 2 4 _aMolecular Medicine.
700 1 _aDalton, John P.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441984135
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v712
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-8414-2
912 _aZDB-2-SBL
999 _c105991
_d105991