| 000 | 02975nam a22005055i 4500 | ||
|---|---|---|---|
| 001 | 978-1-4419-7856-1 | ||
| 003 | DE-He213 | ||
| 005 | 20140220083725.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 101216s2011 xxu| s |||| 0|eng d | ||
| 020 |
_a9781441978561 _9978-1-4419-7856-1 |
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| 024 | 7 |
_a10.1007/978-1-4419-7856-1 _2doi |
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| 050 | 4 | _aRM1-950 | |
| 072 | 7 |
_aMMG _2bicssc |
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| 072 | 7 |
_aMED071000 _2bisacsh |
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| 082 | 0 | 4 |
_a615 _223 |
| 100 | 1 |
_aHickey, Anthony J. _eauthor. |
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| 245 | 1 | 0 |
_aPharmaco-Complexity _h[electronic resource] : _bNon-Linear Phenomena and Drug Product Development / _cby Anthony J. Hickey, Hugh D.C. Smyth. |
| 250 | _a1. | ||
| 264 | 1 |
_aBoston, MA : _bSpringer US : _bImprint: Springer, _c2011. |
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| 300 |
_aVIII, 71p. 9 illus., 2 illus. in color. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
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| 490 | 1 |
_aOutlines in Pharmaceutical Sciences, _x2191-3188 ; _v1 |
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| 505 | 0 | _aThe nature of complexity and relevance to the pharmaceutical sciences -- Phenomena in Physical and Surface Chemistry -- Solid State Pharmaceuticals: Solving Complex Problems in Preformulation and Formulation -- Considerations in monitoring and controlling pharmaceutical manufacturing -- Pharmacokinetics and pharmacodynamics -- Impact of complexity on population Biology -- Conclusion. . | |
| 520 | _aThe historical approach to the interpretation of physical, chemical and biological phenomena has been to consider relationships with causative factors that can be reduced to linearity allowing simple and direct interpretation. However, it is increasingly evident that there is often more information in the data than linear interpretations allow. The current capacity for computers to assist in identifying non-linear relationships allows greater interpretation of data which illuminates the phenomena allowing the information to be translated into knowledge that can be used wisely to promote various desirable pharmaceutical outcomes. This short volume is intended to stimulate the reader to contemplate research and development areas in which the data might be more accurately interpreted to allow greater understanding and ultimately control of the pharmaceutically complex phenomena. | ||
| 650 | 0 | _aMedicine. | |
| 650 | 0 | _aToxicology. | |
| 650 | 0 | _aBiotechnology. | |
| 650 | 0 | _aBiochemistry. | |
| 650 | 1 | 4 | _aBiomedicine. |
| 650 | 2 | 4 | _aPharmacology/Toxicology. |
| 650 | 2 | 4 | _aBiotechnology. |
| 650 | 2 | 4 | _aBiochemistry, general. |
| 700 | 1 |
_aSmyth, Hugh D.C. _eauthor. |
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| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9781441978554 |
| 830 | 0 |
_aOutlines in Pharmaceutical Sciences, _x2191-3188 ; _v1 |
|
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-1-4419-7856-1 |
| 912 | _aZDB-2-SBL | ||
| 999 |
_c105875 _d105875 |
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