000 04070nam a22005175i 4500
001 978-1-4419-6558-5
003 DE-He213
005 20140220083721.0
007 cr nn 008mamaa
008 101029s2011 xxu| s |||| 0|eng d
020 _a9781441965585
_9978-1-4419-6558-5
024 7 _a10.1007/978-1-4419-6558-5
_2doi
050 4 _aRC321-580
072 7 _aPSAN
_2bicssc
072 7 _aMED057000
_2bisacsh
082 0 4 _a612.8
_223
100 1 _aCanepari, Marco.
_eeditor.
245 1 0 _aMembrane Potential Imaging in the Nervous System
_h[electronic resource] :
_bMethods and Applications /
_cedited by Marco Canepari, Dejan Zecevic.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2011.
300 _aX, 170p. 95 illus., 71 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aHistorical overview and general methods of membrane potential imaging -- Design and use of organic voltage sensitive dyes -- Imaging submillisecond membrane potential changes from individual regions of single axons, dendrites and spines -- Combined voltage and calcium imaging and signal calibration -- Use of fast-responding voltage-sensitive dyes for large-scale recording of neuronal spiking activity with single-cell resolution -- Monitoring integrated activity of individual neurons using FRET-based voltage-sensitive dyes -- Monitoring population membrane potential signals from neocortex -- Monitoring population membrane potential signals during functional development of neuronal circuits in vertebrate embryos -- Imaging the dynamics of mammalian neocortical population activity in-vivo -- Imaging the dynamics of neocortical population activity in behaving and freely moving mammals -- Monitoring membrane voltage using two-photon excitation of fluorescent voltage-sensitive dyes -- Random-access multiphoton microscopy for fast three-dimensional Imaging -- Second harmonic imaging of membrane potential -- Genetically encoded protein sensors of membrane potential.
520 _aMembrane Potential Imaging in the Nervous System: Methods and Applications describes optical techniques to monitor neuronal membrane potential signals. The knowledge upon which voltage-imaging technique is based was generated over several decades and the aim of this book is to provide a single comprehensive source of information on different types of voltage-imaging techniques, including overviews, methodological details, examples of experimental measurements, and future developments. The book is structured in five sections, each containing several chapters written by experts and major contributors to particular topics. The volume starts with a historical perspective and fundamental principles of membrane potential imaging and continues to cover the measurement of membrane potential signals from dendrites and axons of individual neurons, measurements of the activity of many neurons with single cell resolution, monitoring of population signals from the nervous system, and concludes with the overview of new approaches to voltage-imaging. Membrane Potential Imaging in the Nervous System is targeted at all scientists interested in this mature but also rapidly expanding imaging approach.
650 0 _aMedicine.
650 0 _aHuman physiology.
650 0 _aNeurosciences.
650 0 _aNeurobiology.
650 0 _aMicroscopy.
650 0 _aCytology
_xResearch_xMethodology.
650 1 4 _aBiomedicine.
650 2 4 _aNeurosciences.
650 2 4 _aHuman Physiology.
650 2 4 _aNeurobiology.
650 2 4 _aBiological Techniques.
650 2 4 _aBiological Microscopy.
700 1 _aZecevic, Dejan.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441965578
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-6558-5
912 _aZDB-2-SBL
999 _c105620
_d105620