000 04086nam a22004815i 4500
001 978-1-4419-6082-5
003 DE-He213
005 20140220083720.0
007 cr nn 008mamaa
008 101109s2011 xxu| s |||| 0|eng d
020 _a9781441960825
_9978-1-4419-6082-5
024 7 _a10.1007/978-1-4419-6082-5
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aWang, Xin Wei.
_eeditor.
245 1 0 _aMolecular Genetics of Liver Neoplasia
_h[electronic resource] /
_cedited by Xin Wei Wang, Joe W. Grisham, Snorri S. Thorgeirsson.
264 1 _aNew York, NY :
_bSpringer New York,
_c2011.
300 _aXIV, 399 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCancer Genetics
505 0 _aPart I: Introduction -- 1. Overview of HCC: biology and pathology -- Xin Wei Wang, Joe Grisham and Snorri Thorgeirsson -- 2. Overview of CC: -- Part II: Liver development and pathogenesis -- 3. Embryonic development of the liver -- Kenneth S. Zaret -- 4. Human hepatic cell lineages -- Nelson Fausto -- 5. Pathology of Human Liver Cancer -- Masamichi Kojiro -- Part III: Genetics and epidemiology of liver cancer -- 6. HCC -- Hashem El.Serag -- 7. CC -- Greg Gores -- Part IV: Molecular Basis of Cancer Susceptibility -- 8. Yusuke Nakamura (NCC) -- 9. Hereditary liver diseases with a high risk to develop HCC -- Markus Grompe, [ALSO Marie-Annick Buendia] -- 10. Genetics and epigenetics of preneoplastic liver diaseses and human HCC -- 11. HBV: Jack Wands -- 12. HCV: Stanly Lemon -- 13. Fibrosis and cirrhosis studies -- David Brenner -- 14. Methylation status in chronic liver disease and HCC -- Yae Kanai (Japan) -- Part V. Animal models -- 15. Transgenic mouse models -- Snorri Thorgeirsson & Joe Grisham -- 16. Mosaic mouse model -- Scott Lowe -- 17. Zebrafish model -- Zhiyuan Gong (NUS): -- Part VI: Global gene expression profiling of human liver cancer -- 18. Integrative and functional genomics of HCC -- Snorri Thorgeirsson: -- 19. Molecular signatures of metastatic HCC -- Xin Wei Wang -- 20. Liver cancer heterogeneity and tumor subtypes -- Jessica Rossi -- 21. Gene expression studies in cholangiocarcinoma -- Yoichi Furokawa -- Part VII: Cancer stem cells -- 22. Snorri Thorgeirsson -- 23. Tania Roskams -- Part VIII: Liver cancer genetics in the clinic -- 24. Biomarkers and clinical staging of liver cancer -- Josep Llovet -- 25. Molecular signaling in HCC -- Hong Yang Wang (Shanghai) -- 26. Molecular oncology and HCC -- Zhao-You Tang (Shanghai) -- 27. Molecular pathogenesis of HCC -- Irene Ig (Hong Kong).
520 _aCancer is a genetic disease and cancer research is a broad discipline embracing investigators and clinicians with diverse backgrounds. This new edition of Molecular Genetics of Liver Neoplasia intends to provide a comprehensive view on genetics and a mechanistic understanding of liver cancer. The book covers from molecular pathogenesis and cellular origin to translational genomics of liver cancer. The leading experts in the field of liver cancer have thoroughly summarized the latest developments and have provided current viewpoints and novel concepts. This cutting-edge volume is a vital resource for today’s basic cancer researchers, graduate students, medical students and clinicians interested in hepatocarcinogenesis.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aToxicology.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aPharmacology/Toxicology.
700 1 _aGrisham, Joe W.
_eeditor.
700 1 _aThorgeirsson, Snorri S.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781441960818
830 0 _aCancer Genetics
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4419-6082-5
912 _aZDB-2-SBL
999 _c105579
_d105579