000 03261nam a22004575i 4500
001 978-0-85729-293-3
003 DE-He213
005 20140220083713.0
007 cr nn 008mamaa
008 110523s2011 xxk| s |||| 0|eng d
020 _a9780857292933
_9978-0-85729-293-3
024 7 _a10.1007/978-0-85729-293-3
_2doi
050 4 _aRC648-665.2
072 7 _aMJG
_2bicssc
072 7 _aMED027000
_2bisacsh
082 0 4 _a616.4
_223
100 1 _aDuque, Gustavo.
_eeditor.
245 1 0 _aOsteoporosis Research
_h[electronic resource] :
_bAnimal Models /
_cedited by Gustavo Duque, Ken Watanabe.
264 1 _aLondon :
_bSpringer London,
_c2011.
300 _aXIX, 196p. 72 illus., 34 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aHow to select your animal model for osteoporosis research -- Skeletal phenotyping in rodents: tissue isolation and manipulation -- Methods in bone biology in animals – Biomechanics -- Methods in Bone Histomorphometry for Animal Models -- Methods in bone biology in animals -- Methods in bone biology in animals - Biochemical markers -- Methods in Bone Biology: Cancer and Bone -- How to test osteoporosis treatments in experimental animals -- The ovariectomized mice and rats -- Classical Models of Senile Osteoporosis -- Animal Models of Premature Aging -- Non-human primate models of osteoporosis -- Other large animal models -- Models for the study of fracture healing and bone regeneration.
520 _aOsteoporosis Research - Animal Models, presents in a very illustrative and practical manner, general methodologies of bone studies in animals, as well as the particular features of the most commonly used animal models in the field. Research in the field of osteoporosis has grown in recent years. This has resulted in significant advances in determining the causes of osteoporosis, assessing risk factors, and creating new treatment methods. The use of animal models provides important knowledge about pathological conditions that can eventually lead to the development of more effective clinical treatment of diseases in both humans and animals.   Osteoporosis Research - Animal Models, is an essential tool for researchers in the bone field. This book aids researchers in selecting their appropriate model and highlights the experiments that can be strategically designed to optimize the potential of an animal to develop the cardinal features of osteoporosis in humans. This book addresses the importance of recent findings from animal models and their significance on the pathogenesis of osteoporosis in relation to human disease.
650 0 _aMedicine.
650 0 _aEndocrinology.
650 0 _aOrthopedics.
650 1 4 _aMedicine & Public Health.
650 2 4 _aEndocrinology.
650 2 4 _aOrthopedics.
650 2 4 _aBiomedicine general.
700 1 _aWatanabe, Ken.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780857292926
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-85729-293-3
912 _aZDB-2-SME
999 _c105183
_d105183