000 03964nam a22004095i 4500
001 978-94-007-5237-5
003 DE-He213
005 20140220083348.0
007 cr nn 008mamaa
008 121211s2012 ne | s |||| 0|eng d
020 _a9789400752375
_9978-94-007-5237-5
024 7 _a10.1007/978-94-007-5237-5
_2doi
050 4 _aR-RZ
072 7 _aMBGR
_2bicssc
072 7 _aMED000000
_2bisacsh
082 0 4 _a610
_223
100 1 _aThakur, Mahendra K.
_eeditor.
245 1 0 _aBrain Aging and Therapeutic Interventions
_h[electronic resource] /
_cedited by Mahendra K. Thakur, Suresh I.S. Rattan.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2012.
300 _aXII, 296 p. 36 illus., 16 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aEditorial -- Contributors -- 1 Brain aging: a critical reappraisal -- 2 Base excision DNA repair: the house keeping guardian for genomic stability in the brain -- 3 Role of brain-derived neurotrophic factor as a modulator of synaptic plasticity -- 4 Mitochondrial dysfunction in sporadic Alzheimer's disease: mechanisms, consequences and interventions -- 5 Brain Aging: Influence of early–life events on late-life brain disorders -- 6 The importance of the environment in brain aging: Be happy, live longer -- 7 Consequences of altered mortalin expression in control of cell proliferation and brain function -- 8 Age induced alterations in biological clock : Therapeutic effects of melatonin changes in regulation of biological clock -- 9 Neurolipofuscin in aging and aluminum-induced aging: Possible therapeutic interventions -- 10 Dietary restriction as a potential intervention to retard age-associated impairment of brain functions -- 11 Understanding mechanism of action of herbal drugs in age-related degenerative brain disorders -- 12 Neurodegeneration in hypoxia: implications in aging -- 13 Stress and memory; from mechanisms to long-lasting consequences -- 14 Estrogen mediated neuroprotection: Hope to combat neuronal degeneration and synaptic plasticity post-menopause -- 15 Potential therapeutic targets for memory impairments and dementia: Clues obtained from memory-enhanced mice -- 16 Potential beneficial effects of a diet with walnuts in aging and Alzheimer’s disease -- 17 Smart dietary interventions and prevention of cognitive decline with aging -- 18 Herbal cognitive enhancers: New developments and challenges for therapeutic applications -- Index.
520 _aThe proposed book will be a multi-author review book comprised of relevant chapters written in the form of critical reviews by the leading researchers in their respective fields. The format of the articles will be in semi-academic style in which research data from various experimental systems will be presented while focusing on their applications in human beings with respect to the prevention and treatment of age-related impairments in brain functions. The book will consist of about 18 chapters, each of which will be on an average 16 pages long giving about 300 pages. Each chapter will be a comprehensive and critical review of the topic in question presenting important data in a tabulated form, and wherever necessary using photographs and line drawings. It will provide an authoritative and up-to-date account of a specific topic with a comprehensive list of citations of original research papers and review articles.
650 0 _aMedicine.
650 1 4 _aBiomedicine.
650 2 4 _aBiomedicine general.
700 1 _aRattan, Suresh I.S.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789400752368
856 4 0 _uhttp://dx.doi.org/10.1007/978-94-007-5237-5
912 _aZDB-2-SBL
999 _c104851
_d104851