000 | 02621nam a22005055i 4500 | ||
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001 | 978-94-007-4216-1 | ||
003 | DE-He213 | ||
005 | 20140220083346.0 | ||
007 | cr nn 008mamaa | ||
008 | 120404s2012 ne | s |||| 0|eng d | ||
020 |
_a9789400742161 _9978-94-007-4216-1 |
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024 | 7 |
_a10.1007/978-94-007-4216-1 _2doi |
|
050 | 4 | _aRC261-271 | |
072 | 7 |
_aMJCL _2bicssc |
|
072 | 7 |
_aMED062000 _2bisacsh |
|
082 | 0 | 4 |
_a614.5999 _223 |
100 | 1 |
_aBerencsi III, György. _eeditor. |
|
245 | 1 | 0 |
_aMaternal Fetal Transmission of Human Viruses and their Influence on Tumorigenesis _h[electronic resource] / _cedited by György Berencsi III. |
264 | 1 |
_aDordrecht : _bSpringer Netherlands, _c2012. |
|
300 |
_aVIII, 464p. 18 illus. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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520 | _aThe human foetus is separated from the maternal blood by the syncytiotrophoblast induced by endogeneous human retrovirus-encoded proteins. This barrier is a highly developed one, which suppors apical-basolateral transport of maternal idiotype and anti-idiotype IgG, IgG-virus complexes. The selective maternal-fetal transport of epitope- and paratope-bearing entities can influence the developping fetal immune system during pregnancy. The bidirectional maternal-fetal transfer of cells are of even more importance during pregnancy. Maternal cells with latent viruses transport viruses without impairment of fetal development. Cells with premaligant and malignant genetic transformation are also transported to the fetus. Fetal and neonatal tumours are initiated by such cells in spite of the antitumour potential of fetal organism. On the contary, the fetal cells repair maternal tissue injouries and survive in the organisms of the recipients for decades. These possess new consequences for the neonatal immunity and organ transplatation surgery. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aOncology. | |
650 | 0 | _aImmunology. | |
650 | 0 | _aMedical virology. | |
650 | 0 | _aPediatrics. | |
650 | 0 | _aEpidemiology. | |
650 | 1 | 4 | _aBiomedicine. |
650 | 2 | 4 | _aCancer Research. |
650 | 2 | 4 | _aVirology. |
650 | 2 | 4 | _aImmunology. |
650 | 2 | 4 | _aOncology. |
650 | 2 | 4 | _aPediatrics. |
650 | 2 | 4 | _aEpidemiology. |
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9789400742154 |
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-94-007-4216-1 |
912 | _aZDB-2-SBL | ||
999 |
_c104735 _d104735 |