000			02884nam a22005295i 4500
001			978-94-007-4186-7
003			DE-He213
005			20140220083346.0
007			cr nn 008mamaa
008			130228s2012 ne | s |||| 0|eng d
020			_a9789400741867 _9978-94-007-4186-7
024	7		_a10.1007/978-94-007-4186-7 _2doi
050		4	_aR-RZ
072		7	_aMBGR _2bicssc
072		7	_aMED000000 _2bisacsh
082	0	4	_a610 _223
100	1		_aHarris, Tony. _eeditor.
245	1	0	_aAdherens Junctions: from Molecular Mechanisms to Tissue Development and Disease _h[electronic resource] / _cedited by Tony Harris.
264		1	_aDordrecht : _bSpringer Netherlands : _bImprint: Springer, _c2012.
300			_aVI, 431 p. 58 illus., 55 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aSubcellular Biochemistry, _x0306-0225 ; _v60
520			_aCell–cell adhesion is fundamental for the development and homeostasis of animal tissues and organs.  Adherens junctions (AJs) are the best understood cell-cell adhesion complexes.  In this volume, internationally recognized experts review AJ biology over a wide range of organization; from atoms to molecules, to protein complexes, molecular networks, cells, tissues, and overall animal development.  AJs have also been an integral part of animal evolution, and play central roles in cancer development, pathogen infection and other diseases.  This book addresses major questions encompassing AJ biology. - How did AJs evolve? - How do cadherins and catenins interact to assemble AJs and mediate adhesion? - How do AJs interface with other cellular machinery to couple adhesion with the whole cell? - How do AJs affect cell behaviour and multicellular development? - How can abnormal AJ activity lead to disease? Valuable for both newcomers and experts in the field, this book offers a comprehensive resource for the research laboratory and a teaching tool for advanced undergraduate and graduate courses in cell and developmental biology.
650		0	_aMedicine.
650		0	_aOncology.
650		0	_aBiochemistry.
650		0	_aCell receptors.
650		0	_aCytology.
650		0	_aDevelopmental biology.
650	1	4	_aBiomedicine.
650	2	4	_aBiomedicine general.
650	2	4	_aCell Biology.
650	2	4	_aDevelopmental Biology.
650	2	4	_aProtein Structure.
650	2	4	_aReceptors.
650	2	4	_aCancer Research.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9789400741850
830		0	_aSubcellular Biochemistry, _x0306-0225 ; _v60
856	4	0	_uhttp://dx.doi.org/10.1007/978-94-007-4186-7
912			_aZDB-2-SBL
999			_c104730 _d104730