000 03839nam a22005055i 4500
001 978-94-007-2828-8
003 DE-He213
005 20140220083343.0
007 cr nn 008mamaa
008 120206s2012 ne | s |||| 0|eng d
020 _a9789400728288
_9978-94-007-2828-8
024 7 _a10.1007/978-94-007-2828-8
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aHayat, M.A.
_eeditor.
245 1 0 _aStem Cells and Cancer Stem Cells, Volume 4
_h[electronic resource] :
_bTherapeutic Applications in Disease and Injury /
_cedited by M.A. Hayat.
264 1 _aDordrecht :
_bSpringer Netherlands,
_c2012.
300 _aXIX, 319p. 44 illus., 32 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aStem Cells and Cancer Stem Cells ;
_v4
520 _aIt is difficult to overstate the potential applications of stem-cell biology to our understanding of, and responses to, disease and injury. This volume aims to bring to its readers authoritative and responsive coverage of aspects of the field that will keep them up-to-date in a fast-moving scientific landscape. The fourth volume in the series on stem cells and their cancer-carrying counterparts, this book sets out the plethora of therapeutic applications offered by a group of specific stem cells in tackling disease and tissue injury. The list of subjects includes embryonic, induced pluripotent, human hair follicle, bone marrow-derived human mesenchymal, adipose-derived, cancer, and breast cancer stem cells, in addition to periodontal/progenitor cells. The adaptability of human embryonic stem cells, which have the potential to develop into any cell type, ensures them an especially detailed treatment.   Contributions explore the causal influence of cancer stem cells in malignancies such as cancer and breast cancer, and delineate the way mesenchymal stem cells contribute to the growth and metastasis of colon cancer. Shifting from disease to treatment, the text explains the therapeutic value of transplanting mesenchymal stem cells to the injured brain as an aid to its recovery. It includes material, too, on the exciting prospect of valuable new targeted cancer drugs borne of our increasing understanding of the molecular pathways peculiar to tumor biology. Key topics, such as the benefit of stem cell transplantation to immune system recovery among severe combined immunodeficiency patients, and the treatment of malignant gliomas using genetically modified neural stem cells as markers, provide a window on cutting-edge work in these specialized subjects. The extensive scope and detailed analysis of this volume, and of the series to which it belongs, mean that whether readers want a breakdown of the impact being made by cancer stem cell research on the design of next-generation cancer therapies, or details of the way stem cells could transform regenerative medicine by repairing damage to vital organs and tissues, they will find these—and much more—here.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aMedical laboratories.
650 0 _aNeurosciences.
650 0 _aStem cells.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aOncology.
650 2 4 _aStem Cells.
650 2 4 _aLaboratory Medicine.
650 2 4 _aNeurosciences.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789400728271
830 0 _aStem Cells and Cancer Stem Cells ;
_v4
856 4 0 _uhttp://dx.doi.org/10.1007/978-94-007-2828-8
912 _aZDB-2-SBL
999 _c104581
_d104581