000 | 02365nam a22004935i 4500 | ||
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001 | 978-94-007-2418-1 | ||
003 | DE-He213 | ||
005 | 20140220083341.0 | ||
007 | cr nn 008mamaa | ||
008 | 111101s2012 ne | s |||| 0|eng d | ||
020 |
_a9789400724181 _9978-94-007-2418-1 |
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024 | 7 |
_a10.1007/978-94-007-2418-1 _2doi |
|
050 | 4 | _aRC261-271 | |
072 | 7 |
_aMJCL _2bicssc |
|
072 | 7 |
_aMED062000 _2bisacsh |
|
082 | 0 | 4 |
_a614.5999 _223 |
100 | 1 |
_aHayat, M.A. _eeditor. |
|
245 | 1 | 0 |
_aNeuroblastoma _h[electronic resource] : _bDiagnosis, Therapy, and Prognosis / _cedited by M.A. Hayat. |
264 | 1 |
_aDordrecht : _bSpringer Netherlands, _c2012. |
|
300 |
_aXVIII, 262p. 40 illus., 24 illus. in color. _bonline resource. |
||
336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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490 | 1 |
_aPediatric Cancer, _x2211-7997 ; _v1 |
|
520 | _aIntroduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is also included. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aOncology. | |
650 | 0 | _aRadiology, Medical. | |
650 | 0 | _aPediatrics. | |
650 | 0 | _aSurgery. | |
650 | 1 | 4 | _aBiomedicine. |
650 | 2 | 4 | _aCancer Research. |
650 | 2 | 4 | _aPediatrics. |
650 | 2 | 4 | _aDiagnostic Radiology. |
650 | 2 | 4 | _aPediatric Surgery. |
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9789400724174 |
830 | 0 |
_aPediatric Cancer, _x2211-7997 ; _v1 |
|
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-94-007-2418-1 |
912 | _aZDB-2-SBL | ||
999 |
_c104475 _d104475 |