000			02911nam a22005535i 4500
001			978-88-470-2490-8
003			DE-He213
005			20140220083335.0
007			cr nn 008mamaa
008			120425s2012 it | s |||| 0|eng d
020			_a9788847024908 _9978-88-470-2490-8
024	7		_a10.1007/978-88-470-2490-8 _2doi
050		4	_aQH323.5
050		4	_aQH324.2-324.25
072		7	_aPDE _2bicssc
072		7	_aMAT003000 _2bisacsh
082	0	4	_a570.285 _223
100	1		_aLiu, Weijiu. _eauthor.
245	1	0	_aIntroduction to Modeling Biological Cellular Control Systems _h[electronic resource] / _cby Weijiu Liu.
264		1	_aMilano : _bSpringer Milan, _c2012.
300			_aX, 290p. 61 illus. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aMS&A, _x2037-5255
505	0		_aEnzyme Kinetics -- Preliminary Systems Theory -- Control of Blood Glucose -- Control of Calcium in Yeast Cells -- Kinetics of Ion Pumps and Channels -- Store-Operated Calcium Entry -- Control of Mitochondrial Calcium -- Control of Phosphoinositide Synthesis -- PreliminaryMATLAB.
520			_aThis textbook contains the essential knowledge in modeling, simulation, analysis, and applications in dealing with biological cellular control systems. In particular, the book shows how to use the law of mass balance and the law of mass action to derive an enzyme kinetic model - the Michaelis-Menten function or the Hill function, how to use a current-voltage relation, Nernst potential equilibrium equation, and Hodgkin and Huxley's models to model an ionic channel or pump, and how to use the law of mass balance to integrate these enzyme or channel models into a complete feedback control system. The book also illustrates how to use data to estimate parameters in a model, how to use MATLAB to solve a model numerically, how to do computer simulations, and how to provide model predictions. Furthermore, the book demonstrates how to conduct a stability and sensitivity analysis on a model.
650		0	_aMathematics.
650		0	_aChemistry _xMathematics.
650		0	_aBiological models.
650		0	_aCytology.
650		0	_aDifferential Equations.
650		0	_aSystems theory.
650	1	4	_aMathematics.
650	2	4	_aMathematical and Computational Biology.
650	2	4	_aSystems Biology.
650	2	4	_aMath. Applications in Chemistry.
650	2	4	_aSystems Theory, Control.
650	2	4	_aOrdinary Differential Equations.
650	2	4	_aCell Biology.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9788847024892
830		0	_aMS&A, _x2037-5255
856	4	0	_uhttp://dx.doi.org/10.1007/978-88-470-2490-8
912			_aZDB-2-SMA
999			_c104154 _d104154