000 03567nam a22005175i 4500
001 978-3-642-31785-9
003 DE-He213
005 20140220083323.0
007 cr nn 008mamaa
008 121213s2012 gw | s |||| 0|eng d
020 _a9783642317859
_9978-3-642-31785-9
024 7 _a10.1007/978-3-642-31785-9
_2doi
050 4 _aQR180-189.5
072 7 _aMJCM
_2bicssc
072 7 _aMED044000
_2bisacsh
082 0 4 _a616.079
_223
100 1 _aAghamohammadi, Asghar.
_eeditor.
245 1 0 _aClinical Cases in Primary Immunodeficiency Diseases
_h[electronic resource] :
_bA Problem-Solving Approach /
_cedited by Asghar Aghamohammadi, Nima Rezaei.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2012.
300 _aXIX, 377 p. 31 illus., 19 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aRecurrent infections -- Combined T- and B-cell immunodeficiencies -- Primary Antibody Deficiencies -- Disorders of Phagocytic Cells -- Immune dysregulation diseases -- Defects in Innate immunity: Receptors and Signaling Components -- Autoinflammatory disorders -- Complement deficiencies -- Other well-defined immunodeficiency syndromes.  .
520 _aPrimary immunodeficiency diseases (PIDs) are a heterogeneous group of inherited disorders characterized by different defects in the development and function of the immune system. These defects render patients susceptible to a variety of infectious diseases. Knowledge of normal immunity and specific warning signs and symptoms can help physicians to identify those children with underlying PIDs. This book aims to increase the clinical awareness and knowledge of practicing clinicians regarding the diagnosis and management of PIDs. In order to achieve this goal, about 90 cases drawn from real life are presented, along with approximately 300 related questions. The selected case reports are the result of the invaluable cooperation of more than 40 scientists in the field of immunodeficiency. They focus both on the presenting features of patients with PIDs and on the required further investigation and management. Although the case scenarios relate to real histories, some modifications have been made for educational purposes. Each of the numbered cases is followed by the questions, their answers, and additional discussion. Each question focuses on a particular aspect of the PID under consideration, and the topics covered include clinical diagnosis, laboratory findings, molecular mechanisms, and therapy. This practical, case-oriented book will be an invaluable source of guidance on the diagnosis and treatment of patients with PIDs and will be relevant for those working in a variety of specialties and subspecialties.
650 0 _aMedicine.
650 0 _aHuman genetics.
650 0 _aImmunology.
650 0 _aAllergy.
650 0 _aEmerging infectious diseases.
650 0 _aPediatrics.
650 1 4 _aBiomedicine.
650 2 4 _aImmunology.
650 2 4 _aAllergology.
650 2 4 _aPediatrics.
650 2 4 _aInfectious Diseases.
650 2 4 _aHuman Genetics.
700 1 _aRezaei, Nima.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642317842
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-31785-9
912 _aZDB-2-SBL
999 _c103411
_d103411