000			03188nam a22005175i 4500
001			978-3-642-30526-9
003			DE-He213
005			20140220083319.0
007			cr nn 008mamaa
008			120731s2012 gw | s |||| 0|eng d
020			_a9783642305269 _9978-3-642-30526-9
024	7		_a10.1007/978-3-642-30526-9 _2doi
050		4	_aQR46
072		7	_aMMFM _2bicssc
072		7	_aMED052000 _2bisacsh
082	0	4	_a616.9041 _223
100	1		_aChatterjee, S.N. _eauthor.
245	1	0	_aOuter Membrane Vesicles of Bacteria _h[electronic resource] / _cby S.N. Chatterjee, Keya Chaudhuri.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2012.
300			_aIX, 161 p. 29 illus., 10 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aSpringerBriefs in Microbiology, _x2191-5385
505	0		_aDiscovery of outer membrane vesicles: A revisit to the contemporary works -- Gram-negative bacteria: The cell membranes and the outer membrane vesicles -- Factors affecting production of outer membrane vesicles -- Outer membrane vesicles as carriers of biomaterials -- Outer membrane vesicles and the biofilm formation -- Outer membrane vesicles: Interaction with prokaryotes and eukaryotes -- Biogenesis of outer membrane vesicles -- Release of outer membrane vesicles: Is it a novel secretion mechanism ?- Outer membrane vesicles: Physiological and medical applications -- Concluding notes.
520			_aThis book provides a detailed account of the physico-chemical properties and biological functions of the outer membrane vesicles (OMVs) of different pathogenic and non-pathogenic Gram-negative bacteria. It also includes an authentic record of the first systematic study that discovered the mechanism of OMV formation by a pathogen, Vibrio cholerae, and proposed that the process represented a novel secretory activity of bacteria. Furthermore, the authors present clinical and laboratory data on the use of OMVs as immunogens, as effective and licensed vaccines against Neisseria meningitidis serogroup B infections and on the development of more effective vaccines against other human and animal pathogens including Vibrio cholerae. This volume thus bears witness to the emerging revolution in the field of vaccines against pathogens and closes with a discussion of open questions and future research on OMVs.
650		0	_aMedicine.
650		0	_aImmunology.
650		0	_aMicrobiology.
650		0	_aCell membranes.
650		0	_aBacteriology.
650	1	4	_aBiomedicine.
650	2	4	_aMedical Microbiology.
650	2	4	_aImmunology.
650	2	4	_aBacteriology.
650	2	4	_aMembrane Biology.
700	1		_aChaudhuri, Keya. _eauthor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783642305252
830		0	_aSpringerBriefs in Microbiology, _x2191-5385
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-642-30526-9
912			_aZDB-2-SBL
999			_c103197 _d103197