| 000 | 02633nam a22005055i 4500 | ||
|---|---|---|---|
| 001 | 978-3-642-30517-7 | ||
| 003 | DE-He213 | ||
| 005 | 20140220083319.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 120707s2012 gw | s |||| 0|eng d | ||
| 020 |
_a9783642305177 _9978-3-642-30517-7 |
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| 024 | 7 |
_a10.1007/978-3-642-30517-7 _2doi |
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| 050 | 4 | _aQH505 | |
| 072 | 7 |
_aPHVN _2bicssc |
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| 072 | 7 |
_aPHVD _2bicssc |
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| 072 | 7 |
_aSCI009000 _2bisacsh |
|
| 082 | 0 | 4 |
_a571.4 _223 |
| 100 | 1 |
_aOuldridge, Thomas E. _eauthor. |
|
| 245 | 1 | 0 |
_aCoarse-Grained Modelling of DNA and DNA Self-Assembly _h[electronic resource] / _cby Thomas E. Ouldridge. |
| 264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2012. |
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| 300 |
_aXI, 176 p. 44 illus., 25 illus. in color. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
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| 490 | 1 |
_aSpringer Theses, Recognizing Outstanding Ph.D. Research, _x2190-5053 |
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| 505 | 0 | _aA Novel DNA Model -- Methods -- Finite Size Effects -- Structural and Mechanical Properties of Model DNA -- Thermodynamic Properties of Model DNA -- Modelling DNA Tweezers -- Modelling a DNA Walker. | |
| 520 | _aThis thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology. | ||
| 650 | 0 | _aPhysics. | |
| 650 | 0 | _aPolymers. | |
| 650 | 0 | _aNanotechnology. | |
| 650 | 1 | 4 | _aPhysics. |
| 650 | 2 | 4 | _aBiophysics and Biological Physics. |
| 650 | 2 | 4 | _aNanotechnology. |
| 650 | 2 | 4 | _aPolymer Sciences. |
| 650 | 2 | 4 | _aStatistical Physics, Dynamical Systems and Complexity. |
| 650 | 2 | 4 | _aSoft and Granular Matter, Complex Fluids and Microfluidics. |
| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9783642305160 |
| 830 | 0 |
_aSpringer Theses, Recognizing Outstanding Ph.D. Research, _x2190-5053 |
|
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-642-30517-7 |
| 912 | _aZDB-2-PHA | ||
| 999 |
_c103196 _d103196 |
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